Lipofundina Mct/Lct

Soya-Bean Oil Refined, the active ingredient in Lipofundina MCT/LCT, is a parenteral lipid emulsion presented as an intravenous solution for use in patients requiring nutritional support. It provides calories and essential fatty acids for individuals who cannot receive enteral feeding.

GNH USA supplies Lipofundina MCT/LCT as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, transplant centres, oncology centres, pharmacies and clinics worldwide.

Lipofundina MCT/LCT is used as an intravenous lipid emulsion in total parenteral nutrition to supply energy and essential fatty acids.

- Total parenteral nutrition (TPN): provides caloric density and essential fatty acids for patients unable to receive enteral feeding. - Prevention of essential fatty acid deficiency: supplies linoleic and alpha‑linolenic acids during long‑term parenteral therapy. - Support in postoperative or trauma care: delivers rapid energy to patients with increased metabolic demand.

Lipofundina MCT/LCT may be associated with a range of infusion‑related reactions.

Common Side Effects: - Hypertriglyceridaemia: elevated serum triglyceride levels. - Fever or chills during infusion. - Infusion site pain or erythema. - Nausea or vomiting. - Headache. - Mild respiratory discomfort.

Serious or Rare Side Effects: - Fat overload syndrome: severe hyperlipidaemia with organ dysfunction. - Acute pancreatitis. - Anaphylactic or severe allergic reactions. - Hepatic dysfunction or cholestasis. - Pulmonary embolism from lipid droplets. - Sepsis related to contaminated product.

When using Lipofundina MCT/LCT, clinicians should observe several safety measures.

- Monitor triglyceride levels: check serum triglycerides regularly during therapy. - Assess liver function: watch for hepatic enzyme elevations. - Evaluate for fat metabolism disorders: avoid in patients with severe hyperlipidaemia or known lipid metabolism defects. - Check for soy or egg allergy: contraindicated in individuals with hypersensitivity to soy‑derived products. - Use aseptic technique: prevent microbial contamination during preparation and administration. - Store at 2-8°C: keep refrigerated, protect from light, do not freeze or shake.

Lipofundina MCT/LCT can interact with other agents that affect lipid metabolism or share a lipid carrier.

Major Interactions (Avoid): - Concomitant lipid emulsions (e.g., propofol): risk of cumulative fat load and severe hypertriglyceridaemia. - Heparin therapy: may increase lipoprotein lipase activity, altering triglyceride clearance.

Moderate Interactions (Monitor Closely): - Fibrates or statins: potential additive effect on serum lipid levels. - High‑dose glucose infusions: may exacerbate hypertriglyceridaemia. - Immunosuppressants (e.g., cyclosporine): monitor liver function as both can affect hepatic metabolism. - Vitamin E supplementation: may mask oxidative stress signs. - Anticoagulants: monitor coagulation parameters as lipid emulsions can affect platelet function.