Lipiodol Ultra-Fluide

Ethyl esters of iodised fatty acids, the active ingredient in Lipiodol Ultra-Fluide, is an iodinated contrast media presented as an oil‑based solution for intralymphatic use. It enhances radiographic visualization of lymphatic structures and is employed in diagnostic procedures such as lymphangiography, detection of lymphatic leaks, and sentinel lymph node mapping.

GNH USA supplies Lipiodol Ultra-Fluide as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, transplant centres, oncology centres, pharmacies and clinics worldwide.

Lipiodol Ultra-Fluide, an iodinated contrast media used in lymphatic imaging, is indicated for the following clinical applications: - Lymphangiography: provides detailed radiopaque visualization of lymphatic vessels and nodes. - Detection of lymphatic leaks: highlights sites of lymphatic leakage for diagnostic and interventional planning. - Sentinel lymph node mapping: delineates sentinel nodes to guide surgical oncology procedures.

Adverse reactions to Lipiodol Ultra-Fluide may occur following intralymphatic administration.

Common Side Effects: - Pain at injection site: mild discomfort or tenderness. - Local erythema: redness around the injection area. - Transient fever: low‑grade temperature rise lasting a few hours. - Nausea: occasional mild nausea reported.

Serious or Rare Side Effects: - Embolization: blockage of lymphatic or vascular structures. - Allergic reaction: urticaria, bronchospasm, or anaphylaxis. - Pulmonary oil embolism: rare but severe respiratory compromise. - Tissue necrosis: localized tissue death at injection site.

When using Lipiodol Ultra-Fluide, clinicians should observe the following precautions. - Patient assessment: evaluate for iodine allergy or prior contrast reactions. - Renal function: consider renal impairment as iodine load may affect kidney function. - Pregnancy status: avoid use unless benefits outweigh potential risks. - Breastfeeding: discontinue breastfeeding if administered to lactating patients. - Injection technique: use aseptic technique and proper intralymphatic placement to minimize complications. - Store at ambient temperature: keep below 25 °C, protect from light and moisture in original container.

Lipiodol Ultra-Fluide may interact with the following agents.

Major Interactions (Avoid): - Iodine‑containing medications: concurrent high‑dose iodine compounds can increase total iodine load and risk of toxicity. - Anticoagulants: may exacerbate bleeding if vascular injury occurs during injection.

Moderate Interactions (Monitor Closely): - Thyroid hormones: excess iodine can alter thyroid function tests. - Diuretics: may affect renal clearance of iodine. - Radiopharmaceuticals: overlapping imaging agents can interfere with diagnostic interpretation.