Lipiodol Ultra Fluid

Ethyl esters of iodised fatty acids from poppyseed oil, the active ingredient in Lipiodol Ultra Fluid, is an iodinated oil‑based contrast agent presented as an oil‑based liquid for intraglandular, intralymphatic and intrauterine use. It provides radiopaque contrast for imaging procedures such as lymphangiography, hysterosalpingography and selected embolisation interventions.

GNH USA supplies Lipiodol Ultra Fluid as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, transplant centres, oncology centres, pharmacies and clinics worldwide.

Lipiodol Ultra Fluid, an iodinated oil‑based contrast medium, is used in radiographic procedures that require high‑density contrast.

Lymphangiography: visualises lymphatic vessels and nodes to assess obstruction or leakage. Hysterosalpingography: delineates uterine cavity and fallopian tube patency for fertility evaluation. Embolisation procedures: provides temporary occlusion of target vessels during therapeutic embolisation. Selected intra‑arterial or intra‑venous contrast enhancement: enhances vascular imaging in specialised radiologic examinations.

Adverse reactions may occur following administration of Lipiodol Ultra Fluid.

Common Side Effects: - Mild pain or burning at the injection site. - Transient fever or chills. - Nausea or vomiting. - Headache. - Skin erythema or mild rash. - Temporary taste alteration.

Serious or Rare Side Effects: - Anaphylactic or severe allergic reaction. - Pulmonary embolism or oil‑induced lung injury. - Thyroid dysfunction due to iodine overload. - Acute renal impairment. - Embolic events causing tissue ischemia. - Severe hypotension or cardiovascular collapse.

Prior to use, clinicians should evaluate patient history and procedural requirements. - Assess iodine allergy: screen for known hypersensitivity to iodinated contrast agents. - Evaluate thyroid status: consider recent iodine exposure or thyroid disease. - Monitor renal function: avoid in patients with severe renal impairment unless benefits outweigh risks. - Use appropriate technique: ensure correct injection site and volume to minimise embolic risk. - Store at ambient temperature: keep container tightly closed, protect from light and heat, store below 25 °C.

Lipiodol Ultra Fluid may interact with other medications that affect iodine handling or renal clearance.

Major Interactions (Avoid): - Lithium therapy: increased risk of lithium toxicity. - Radioactive iodine treatment: reduced efficacy due to iodine load. - Thyroid hormone replacement: potential alteration of thyroid function.

Moderate Interactions (Monitor Closely): - Beta‑blockers: may mask tachycardia from contrast reactions. - Diuretics: can affect renal clearance of iodine. - Anticoagulants: heightened risk of bleeding at injection sites.