GNH USA

Europe — EMA

Lipigan (Atorvastatin)

GNH USA supplies Lipigan (Atorvastatin), a lipid‑lowering agent for hypercholesterolemia and cardiovascular risk reduction. Request a quote for global supply.

Atorvastatin

Request sourcing

1
Pack/s

What is Atorvastatin?

Atorvastatin, the active ingredient in Lipigan, is an HMG‑CoA reductase inhibitor presented as a tablet for oral use. It lowers elevated cholesterol and triglyceride levels and is used in adults to manage hypercholesterolemia, mixed dyslipidemia, and to reduce cardiovascular risk, including patients at risk of myocardial infarction and stroke.

GNH USA supplies Lipigan as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide. The company adheres to EU quality standards and provides reliable logistics for global distribution.

What is Atorvastatin used for?

Atorvastatin is a statin medication that acts on lipid metabolism to lower cholesterol. Hypercholesterolemia: reduces LDL‑cholesterol and total cholesterol levels. Mixed dyslipidemia: improves the overall lipid profile by lowering triglycerides and raising HDL‑cholesterol. Cardiovascular disease prevention: decreases the risk of myocardial infarction, stroke and related events in primary and secondary prevention settings.

What are the side effects of Atorvastatin?

Atorvastatin may be associated with a range of adverse reactions, varying from mild to serious.

Common Side Effects: - Headache: mild to moderate headache. - Myalgia: muscle aches without weakness. - Abdominal discomfort: nausea, dyspepsia or stomach pain. - Elevated liver enzymes: mild increase in ALT or AST. - Diarrhea: loose stools. - Fatigue: feeling of tiredness. - Insomnia: difficulty sleeping.

Serious or Rare Side Effects: - Rhabdomyolysis: severe muscle breakdown with possible kidney injury. - Hepatotoxicity: marked elevation of liver enzymes or hepatitis. - Allergic reactions: rash, angioedema or anaphylaxis. - Memory loss: rare reversible cognitive impairment. - Severe liver injury: jaundice or hepatic failure. - Myopathy with weakness: significant muscle weakness accompanied by pain.

What precautions apply to Atorvastatin?

When prescribing Lipigan, several safety considerations are recommended. Pregnancy: contraindicated; teratogenic risk (Category X). Liver disease: avoid in active hepatic impairment. Renal impairment: dose may need adjustment in severe cases. Drug interactions: review concomitant medications for CYP3A4 substrates. Monitoring: periodic liver function tests recommended. Store at ambient temperature: keep below 25 °C, protect from moisture and light.

What does Atorvastatin interact with?

Atorvastatin can interact with a variety of medicines; clinicians should assess the risk before co‑administration.

Major Interactions (Avoid): - Strong CYP3A4 inhibitors (e.g., clarithromycin, itraconazole): can markedly increase atorvastatin levels. - Gemfibrozil: increases risk of myopathy and rhabdomyolysis. - Cyclosporine: raises plasma concentrations, heightening toxicity risk.

Moderate Interactions (Monitor Closely): - Antacids (aluminum, magnesium): may reduce absorption; separate dosing by at least 2 h. - Warfarin: may enhance anticoagulant effect; monitor INR. - Niacin: combined therapy can increase risk of liver enzyme elevation.

Frequently asked questions

What is Lipigan used for?+
Lipigan contains atorvastatin, a statin that is prescribed to lower elevated cholesterol and triglyceride levels. It is indicated for the treatment of hypercholesterolemia, mixed dyslipidemia, and for primary or secondary prevention of cardiovascular events such as heart attack and stroke.
How does atorvastatin work?+
Atorvastatin works by competitively inhibiting the enzyme HMG‑CoA reductase, which is essential for cholesterol synthesis in the liver. This inhibition reduces hepatic cholesterol production, leading to an up‑regulation of LDL receptors and increased clearance of LDL‑cholesterol from the bloodstream, while modestly raising HDL‑cholesterol.
What is the usual dose of Lipigan?+
The appropriate dose of Lipigan is determined by the prescribing clinician based on the patient’s lipid profile, cardiovascular risk, age, and any co‑existing medical conditions. Dosage may be adjusted over time to achieve target cholesterol levels while monitoring safety.
Is Lipigan safe in pregnancy or breastfeeding?+
Lipigan (atorvastatin) is classified as Pregnancy Category X, meaning it is contraindicated during pregnancy because of potential fetal harm. It is also not recommended for breastfeeding mothers, as the drug may be excreted in breast milk and could affect the infant.
How do I order Lipigan from GNH USA?+
To order Lipigan, submit an enquiry on the product page at gnh-usa.com, specifying the required quantity. GNH USA works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.
How does Lipigan compare with other statins?+
Lipigan (atorvastatin) is a high‑potency statin that typically achieves greater reductions in LDL‑cholesterol at lower doses compared with older agents such as simvastatin. Its pharmacokinetic profile includes a longer half‑life, allowing once‑daily dosing, and it is metabolised primarily by CYP3A4, which influences its interaction potential.
How should Lipigan be stored and handled?+
Lipigan tablets should be stored at ambient temperature, preferably below 25 °C, in the original container to protect them from moisture and light. Keep the product out of reach of children and do not use if the packaging is damaged.
How is Lipigan administered?+
Lipigan is taken orally as a whole tablet, usually once daily. It may be taken with or without food; however, consistent administration with respect to meals can help maintain stable drug levels. Swallow the tablet whole with a glass of water.
What are the most serious risks to watch for while taking Lipigan?+
The most serious adverse events associated with Lipigan include rhabdomyolysis (severe muscle breakdown), significant elevations in liver enzymes indicating possible hepatotoxicity, and rare allergic reactions such as anaphylaxis. Patients should report unexplained muscle pain, weakness, dark urine, or jaundice promptly.
Who should not use Lipigan?+
Lipigan should not be used by individuals with active liver disease, unexplained persistent elevations of hepatic transaminases, or those who are pregnant or planning pregnancy. It is also contraindicated in patients with known hypersensitivity to atorvastatin or any component of the formulation.
Information provided on this page is for educational use by procurement and clinical professionals. Always consult a licensed healthcare provider for medical advice and prescribing decisions. GNH USA supplies this product subject to applicable regulatory and licensing requirements.
Send a sourcing enquiry for this product →

Product details

Drug
Atorvastatin
Route
Oral Use
Manufacturer
Medical Pharmaquality Pharmaceuticals S.A.
Origin
EU

Related products

Abator

Abator

Atorvastatin

Sapiens Pharmaceuticals Ltd
EU
Altoram

Altoram

Atorvastatin

Libytec Pharmaceutical S.A.
EU
Amedo

Amedo

Atorvastatin

Medochemie Bohemia, Spol. S R.O.
EU
Amicor

Amicor

Atorvastatin

Medochemie Ltd.
EU