Lipidem

Omega-3-acid triglycerides, the active ingredient in Lipidem, is a parenteral lipid emulsion presented as an intravenous lipid solution for intravenous use. It provides essential fatty acids and calories as an energy source for patients requiring parenteral nutrition, supporting cell membrane integrity and metabolic functions.

GNH USA supplies Lipidem as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, transplant centres and oncology units worldwide.

Lipidem, a parenteral lipid emulsion, is used in clinical nutrition to supply essential fatty acids and calories for patients who cannot receive enteral feeding.

Parenteral nutrition for patients unable to receive enteral feeding: supplies calories and essential fatty acids when oral or tube feeding is not possible. Provision of essential fatty acids in clinical nutrition: supports cell membrane integrity and metabolic functions in critically ill patients. Prevention of essential fatty acid deficiency in long‑term parenteral therapy: maintains adequate fatty acid levels during extended intravenous feeding.

Lipidem may be associated with several adverse reactions following infusion.

Common Side Effects: - Mild fever - Transient hypertriglyceridemia - Infusion site erythema

Serious or Rare Side Effects: - Anaphylactic reaction - Severe hypertriglyceridemia with pancreatitis risk - Fat overload syndrome

When using Lipidem, clinicians should observe specific safety measures.

Assess triglyceride levels before initiation: monitor baseline and periodic serum triglycerides. Monitor liver function tests: watch for hepatic steatosis. Check for allergies to soy or egg phospholipids: avoid in known hypersensitivity. Use caution in patients with pancreatitis history: evaluate risk. Avoid concurrent high‑fat oral intake: may exacerbate hypertriglyceridemia. Store at 2-8°C: keep refrigerated, protect from light, do not freeze or shake.

Lipidem can interact with other medications and therapies; awareness of interaction severity is important.

Major Interactions (Avoid): - Concurrent use of other lipid emulsions: may cause excessive fat load. - High-dose propofol infusion: additive risk of hypertriglyceridemia. - Corticosteroids: can increase triglyceride levels.

Moderate Interactions (Monitor Closely): - Statins: monitor for liver enzyme changes. - Anticoagulants (warfarin): observe INR as lipid infusion may affect plasma protein binding. - Diuretics: watch electrolyte balance due to fluid shifts.