GNH USA

Europe — EMA

Linola Sept

GNH USA supplies Linola Sept (Clioquinol), a topical antiseptic for tinea and other cutaneous fungal infections. Request a quote for global supply.

Clioquinol

Request sourcing

1
Pack/s

What is Clioquinol?

Clioquinol, the active ingredient in Linola Sept, is an antiseptic (topical) presented as a topical formulation for cutaneous (topical) use. It treats superficial fungal and protozoal skin infections such as tinea (ringworm) in both adults and children.

GNH USA supplies Linola Sept as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide. The company adheres to stringent quality standards and provides regulatory‑compliant documentation for global distribution. Its supply chain is designed to meet the needs of diverse healthcare settings across multiple regions.

What is Clioquinol used for?

Clioquinol is used topically to manage fungal and protozoal skin conditions.

- Tinea (ringworm) infections: reduces fungal growth and promotes resolution of skin lesions. - Cutaneous fungal infections: treats dermatophyte‑induced dermatitis and improves skin appearance. - Skin infections caused by susceptible organisms: eliminates susceptible yeasts and protozoa from affected areas.

What are the side effects of Clioquinol?

Clioquinol may cause local skin reactions and, rarely, systemic adverse events.

Common Side Effects: - Skin irritation: mild redness or discomfort at the application site. - Itching: transient pruritus following use. - Burning sensation: brief warmth or stinging. - Erythema: localized redness. - Contact dermatitis: allergic skin response. - Dryness: flaking or scaling of treated skin.

Serious or Rare Side Effects: - Allergic reaction: angioedema or severe swelling. - Severe dermatitis: extensive skin inflammation. - Systemic neurotoxicity: rare neurologic symptoms. - Agranulocytosis: profound reduction in white blood cells. - Photosensitivity: heightened skin reaction to sunlight.

What precautions apply to Clioquinol?

When using Linola Sept, observe the following precautions to ensure safe and effective treatment.

- Avoid application on broken or inflamed skin: may increase irritation. - Do not use on mucous membranes or ocular surfaces: product not intended for these areas. - Discontinue use if severe irritation or allergic reaction occurs: seek medical advice. - Use with caution in children under 2 years: limited safety data. - Limit continuous use to recommended duration: prolonged exposure may cause sensitisation. - Store at room temperature: keep in original container, protect from moisture and light.

What does Clioquinol interact with?

Clioquinol can interact with other agents applied to the skin or affecting metal ion balance.

Major Interactions (Avoid): - Concurrent use with other topical metal‑chelating agents may reduce efficacy. - Use with systemic metal chelators (e.g., deferoxamine) may diminish activity. - Co‑application with strong irritants may increase skin damage.

Moderate Interactions (Monitor Closely): - Combined use with topical corticosteroids may mask irritation signs. - Use with other antifungal creams may alter absorption. - Concurrent use with phototoxic agents may increase risk of photosensitivity.

Frequently asked questions

What is Linola Sept used for?+
Linola Sept is a topical preparation containing clioquinol that is indicated for the treatment of superficial fungal and protozoal skin infections, including tinea (ringworm), other cutaneous fungal infections, and skin conditions caused by susceptible organisms.
How does clioquinol work?+
Clioquinol works by chelating essential metal ions such as iron and zinc, which are required for microbial enzyme activity and membrane stability. This disruption interferes with the metabolism of fungi and protozoa, leading to inhibition of growth and cell death at the site of application.
What is the usual dose of Linola Sept?+
The dosage of Linola Sept is determined by the prescribing healthcare professional. Typically, a thin layer is applied to the affected skin area once or twice daily, following the prescriber’s instructions regarding duration of therapy.
Is Linola Sept safe during pregnancy or breastfeeding?+
Safety data for clioquinol topical use in pregnancy and lactation are limited. Healthcare providers should evaluate the risk‑benefit ratio before prescribing Linola Sept to pregnant or breastfeeding individuals.
How do I order Linola Sept from GNH USA?+
To order Linola Sept, submit an enquiry on the product page at gnh-usa.com, specifying the required quantity. GNH USA works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including any cold‑chain requirements) and the necessary import documentation.
How does Linola Sept compare with the main alternative drug or class?+
Linola Sept (clioquinol) belongs to the topical antiseptic/antifungal class, whereas alternatives such as terbinafine or azole creams act primarily by inhibiting fungal sterol synthesis. Clioquinol’s metal‑chelation mechanism offers a broader spectrum that includes certain protozoa, but clinical choice depends on the specific pathogen, resistance patterns and patient tolerance.
How should Linola Sept be stored and handled?+
Linola Sept should be stored at room temperature, below 25 °C, in its original packaging. Keep the container tightly closed, protect it from moisture and direct sunlight, and avoid freezing. Handling should be performed with clean hands or applicators to maintain product integrity.
How is Linola Sept applied?+
Apply a thin, even layer of Linola Sept to the cleaned, dry skin area affected by infection. Gently rub it in until it disappears, usually once or twice daily as directed by the prescriber. Do not cover the treated area with occlusive dressings unless advised.
What are the most serious risks to watch for?+
Serious adverse reactions, although rare, include severe allergic responses such as angioedema, extensive dermatitis, systemic neurotoxicity, agranulocytosis, and photosensitivity. Patients should seek immediate medical attention if they experience swelling, difficulty breathing, widespread rash, or neurological symptoms.
Who should not use Linola Sept?+
Linola Sept should be avoided in individuals with known hypersensitivity to clioquinol or any excipients in the formulation, on broken or severely inflamed skin, and on mucous membranes or ocular surfaces. Caution is also advised for very young children and patients with compromised immune systems until safety is confirmed by a clinician.
Information provided on this page is for educational use by procurement and clinical professionals. Always consult a licensed healthcare provider for medical advice and prescribing decisions. GNH USA supplies this product subject to applicable regulatory and licensing requirements.

Product details

Drug
Clioquinol
Route
Cutaneous Use
Manufacturer
Dr. August Wolff Gmbh & Co. Kg Arzneimittel
Origin
EU

Related products