Lino

Lisinopril Dihydrate, the active ingredient in Lino, is an angiotensin‑converting enzyme (ACE) inhibitor presented as a tablet for oral use. It treats hypertension and related cardiovascular conditions in adults.

GNH USA supplies Lino as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Lisinopril is an ACE inhibitor used to manage conditions related to the renin‑angiotensin system.

Hypertension: lowers blood pressure and reduces risk of cardiovascular events. Heart failure: improves symptoms and decreases mortality. Post‑myocardial infarction left ventricular dysfunction: supports cardiac remodeling and survival. Diabetic nephropathy: slows progression of kidney disease in diabetic patients.

Lisinopril may cause a range of adverse reactions, from mild to serious.

Common Side Effects: - Cough: dry, persistent throat irritation. - Dizziness or light‑headedness, especially after standing. - Headache. - Fatigue. - Mild hypotension. - Elevated blood potassium.

Serious or Rare Side Effects: - Angioedema: swelling of lips, tongue, or airway. - Severe hypotension: marked drop in blood pressure. - Acute renal impairment or failure. - Neutropenia or leukopenia. - Hepatic dysfunction. - Hyperkalemia leading to cardiac arrhythmia.

Before initiating therapy, consider the following safety measures.

Blood pressure monitoring: check regularly to avoid excessive hypotension. Renal function assessment: evaluate creatinine and eGFR before and during treatment. Electrolyte surveillance: monitor serum potassium levels. Pregnancy considerations: contraindicated in the second and third trimesters (Category D). Drug interaction review: assess concomitant use of NSAIDs, potassium‑sparing agents, and other antihypertensives. Store at ambient temperature: keep below 25°C in the original packaging, protect from moisture.

Lisinopril can interact with several medicines, requiring caution.

Major Interactions (Avoid): - Aliskiren: combined use may increase risk of renal dysfunction and hyperkalemia. - Potassium‑sparing diuretics or supplements: may cause dangerous hyperkalemia. - NSAIDs: can blunt antihypertensive effect and impair renal function.

Moderate Interactions (Monitor Closely): - ARBs (e.g., losartan): additive blood‑pressure lowering, monitor for hypotension. - Thiazide or loop diuretics: may increase risk of hypotension and electrolyte disturbances. - Lithium: may raise lithium levels, requiring serum monitoring.