Lino

Lisinopril, the active ingredient in Lino, is an ACE inhibitor presented as an oral dosage form for oral use. It is prescribed to manage high blood pressure, support heart failure treatment, and improve outcomes after a myocardial infarction in adult patients.

GNH USA supplies Lino as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Lisinopril is used to treat conditions related to the renin‑angiotensin system and cardiovascular disease. - Hypertension: lowers elevated blood pressure and reduces cardiovascular risk. - Heart failure: improves symptoms and functional capacity by decreasing cardiac workload. - Post‑myocardial infarction: helps prevent adverse remodeling and subsequent cardiac events.

Lisinopril may cause a range of adverse reactions, from mild to severe.

Common Side Effects: - Cough: persistent dry cough. - Dizziness: especially when standing quickly. - Headache: mild to moderate intensity. - Fatigue: general tiredness. - Hyperkalemia: elevated blood potassium levels. - Renal function changes: slight increase in serum creatinine.

Serious or Rare Side Effects: - Angioedema: swelling of face, lips, tongue, or airway. - Severe hypotension: markedly low blood pressure. - Acute kidney injury: rapid decline in renal function. - Hepatotoxicity: abnormal liver enzymes. - Neutropenia: low white blood cell count. - Stevens‑Johnson syndrome: severe skin reactions.

Before initiating therapy, consider the following safety measures. - Pregnancy: contraindicated in the second and third trimesters (Category D). - Breastfeeding: use only if benefits outweigh potential risks. - Renal impairment: adjust dose and monitor renal function. - Hyperkalemia: avoid concomitant potassium‑sparing agents. - Hypotension: monitor blood pressure after first dose. - Store at ambient temperature: keep below 25 °C, retain original packaging, protect from moisture.

Lisinopril can interact with several drug classes; awareness helps prevent adverse outcomes.

Major Interactions (Avoid): - Aliskiren: combined use may increase risk of renal dysfunction. - Lithium: may raise lithium levels, risking toxicity. - NSAIDs (e.g., ibuprofen, naproxen): can blunt antihypertensive effect and impair renal function.

Moderate Interactions (Monitor Closely): - Diuretics (especially thiazides): may enhance hypotensive effect. - Potassium supplements or potassium‑sparing diuretics: increase risk of hyperkalemia. - ACE inhibitor or ARB combinations: higher incidence of renal impairment and hyperkalemia.