Linisan

Citalopram hydrobromide, the active ingredient in Linisan, is a selective serotonin reuptake inhibitor presented as an oral tablet for oral use. It is prescribed to treat major depressive disorder in adult patients.

GNH USA supplies Linisan as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide. The company adheres to stringent quality standards, provides batch‑tested products, and supports regulatory compliance for importers across Europe, Asia, Africa and the Americas. Customers benefit from reliable logistics, transparent documentation, and responsive technical assistance throughout the supply chain.

Citalopram hydrobromide is an SSRI that modulates serotonergic pathways in depressive and related mood disorders. - Major depressive disorder: alleviates depressive symptoms and improves mood in adult patients. - Panic disorder: reduces frequency and intensity of panic attacks. - Obsessive‑compulsive disorder: diminishes obsessive thoughts and compulsive behaviors.

Citalopram hydrobromide may cause a range of adverse reactions, varying from mild to severe. Common Side Effects: - Nausea: mild gastrointestinal upset. - Headache: transient cranial discomfort. - Dry mouth: reduced salivation. - Insomnia: difficulty falling or staying asleep. Serious or Rare Side Effects: - Serotonin syndrome: agitation, hyperthermia, muscle rigidity. - QT interval prolongation: risk of cardiac arrhythmia. - Severe allergic reaction: rash, swelling, anaphylaxis.

When prescribing citalopram hydrobromide, clinicians should consider several safety precautions to minimize risk. - Cardiac assessment: evaluate baseline ECG and QT interval, especially in patients with cardiac disease. - Electrolyte monitoring: check serum sodium and potassium levels to prevent hyponatremia. - Serotonin syndrome vigilance: avoid concurrent use of other serotonergic agents. - Discontinuation strategy: taper the dose gradually to reduce withdrawal symptoms. - Elderly caution: start at lower dose and monitor for increased sensitivity. - Store at ambient temperature: keep tablets below 25 °C in the original container, protected from moisture and light.

Citalopram hydrobromide interacts with several medicines; awareness of major and moderate interactions helps ensure safe co‑administration. Major Interactions (Avoid): - Monoamine oxidase inhibitors (MAOIs): risk of severe serotonin syndrome. - Pimozide: can cause cardiac arrhythmias due to QT prolongation. - Linezolid or tramadol: additive serotonergic effects increasing serotonin syndrome risk. Moderate Interactions (Monitor Closely): - NSAIDs and anticoagulants: heightened bleeding tendency. - CYP2C19 inhibitors (e.g., omeprazole): may increase citalopram plasma levels. - Alcohol: can enhance central nervous system depression. - Antihistamines: may increase sedation.