GNH USA

Europe — EMA

Lilia

GNH USA supplies Lilia (Chlormadinone acetate/ethinylestradiol), a combined oral contraceptive for pregnancy prevention and menstrual regulation.

Chlormadinone Acetate, Ethinylestradiol

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What is Chlormadinone Acetate, Ethinylestradiol?

Chlormadinone acetate and ethinylestradiol, the active ingredients in Lilia, are a combined oral contraceptive presented as a tablet for oral use. It prevents pregnancy in women of reproductive age by inhibiting ovulation and creating cervical mucus changes. GNH USA supplies Lilia as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

What is Chlormadinone Acetate, Ethinylestradiol used for?

Lilia is a combined hormonal contraceptive that acts on the hypothalamic‑pituitary‑ovarian axis to prevent pregnancy. - Pregnancy prevention: provides reliable birth control for women of childbearing potential. - Oral contraception: offers a daily oral regimen to inhibit ovulation and fertilisation. - Menstrual cycle regulation: helps achieve more predictable menstrual bleeding patterns.

What are the side effects of Chlormadinone Acetate, Ethinylestradiol?

Lilia may cause a range of adverse reactions, most of which are mild and transient.

Common Side Effects: - Nausea: mild to moderate stomach upset. - Headache: tension‑type or migraine‑like pain. - Breast tenderness: discomfort or swelling of the breasts. - Irregular bleeding: spotting or breakthrough bleeding between periods.

Serious or Rare Side Effects: - Venous thromboembolism: deep‑vein thrombosis or pulmonary embolism. - Hypertension: new‑onset or worsening high blood pressure. - Severe allergic reaction: rash, swelling, or anaphylaxis.

What precautions apply to Chlormadinone Acetate, Ethinylestradiol?

Before prescribing Lilia, clinicians should evaluate individual risk factors and counsel patients on safety considerations. - Contraindicated in pregnancy: product is classified as pregnancy category X and must not be used. - Avoid in smokers over 35 years: increased risk of cardiovascular events. - Assess history of thromboembolic disorders: risk of clot formation may be elevated. - Monitor blood pressure regularly: may cause or worsen hypertension. - Store at ambient temperature: keep in the original pack, protect from moisture and heat.

What does Chlormadinone Acetate, Ethinylestradiol interact with?

Lilia can interact with several medicines that affect hormone metabolism or increase clotting risk.

Major Interactions (Avoid): - Enzyme‑inducing anticonvulsants (e.g., carbamazepine, phenytoin): may reduce contraceptive efficacy. - Strong CYP3A4 inducers (e.g., rifampicin, griseofulvin): can lower hormone levels. - Other estrogen‑containing products (e.g., hormone replacement therapy): may increase estrogen exposure.

Moderate Interactions (Monitor Closely): - Certain antibiotics (e.g., metronidazole): may slightly diminish effectiveness. - Antifungals such as ketoconazole: can increase hormone concentrations. - St. John’s wort herbal supplement: may decrease contraceptive reliability.

Frequently asked questions

What is Lilia used for?+
Lilia is a combined oral contraceptive containing chlormadinone acetate and ethinylestradiol. It is prescribed to prevent pregnancy in women of reproductive age and can also be used to regulate menstrual bleeding patterns as part of family‑planning therapy.
How does chlormadinone acetate/ethinylestradiol work?+
The ethinylestradiol component provides estrogenic activity that stabilises the endometrial lining, while chlormadinone acetate acts as a progestogen. Together they suppress the mid‑cycle surge of luteinising hormone (LH) and follicle‑stimulating hormone (FSH), inhibiting ovulation and inducing cervical mucus changes that impede sperm penetration.
What is the usual dose of Lilia?+
The specific dosing regimen for Lilia is determined by the prescribing clinician based on the product’s labeling and the patient’s individual needs. Typically, combined oral contraceptives are taken once daily for 21 days followed by a hormone‑free interval, but the exact schedule should be confirmed with a qualified health‑care professional.
Is Lilia safe to use during pregnancy or breastfeeding?+
Lilia is classified as pregnancy category X, meaning it must not be used during pregnancy because it can cause fetal harm. It is also not recommended for breastfeeding women, as hormonal contraceptives may affect milk production and expose the infant to estrogen and progestogen. Alternative non‑hormonal methods should be considered in these situations.
How do I order Lilia from GNH USA?+
To place an order, submit an enquiry on the product page at gnh-usa.com, specifying the required quantity of Lilia. GNH USA works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including any required temperature control) and necessary import documentation.
How does Lilia compare with other combined oral contraceptives?+
Lilia contains chlormadinone acetate as the progestogenic component, which is less commonly used than levonorgestrel or desogestrel in many other pills. This may offer a different side‑effect profile, such as lower androgenic activity, but overall efficacy in preventing pregnancy is comparable to other FDA‑approved combined oral contraceptives when taken correctly.
What are the storage requirements for Lilia?+
Lilia tablets should be stored at ambient temperature, below 25 °C (77 °F). Keep them in the original blister pack or container, protect from moisture, heat and direct sunlight, and ensure they are out of reach of children. Do not store in the bathroom or near a kitchen sink where humidity is high.
How is Lilia administered?+
Lilia is taken orally, usually as a tablet taken at the same time each day. The typical regimen involves a 21‑day active tablet sequence followed by a 7‑day pill‑free interval, during which withdrawal bleeding occurs. Patients should swallow the tablet whole with water and should not split or crush it.
What are the most serious risks to watch for with Lilia?+
The most serious risks include venous thromboembolism (deep‑vein thrombosis or pulmonary embolism), arterial thrombosis leading to stroke or myocardial infarction, and severe hypertension. Women with a history of clotting disorders, smoking over age 35, or certain cardiovascular conditions should avoid Lilia and seek alternative contraception.
Who should not use Lilia?+
Lilia is contraindicated in women who are pregnant or suspect they may be pregnant, those with known or suspected estrogen‑dependent tumors, active or history of thromboembolic disease, uncontrolled hypertension, severe liver disease, or who are smokers aged 35 years or older. It should also be avoided in individuals with known hypersensitivity to either chlormadinone acetate or ethinylestradiol.
Information provided on this page is for educational use by procurement and clinical professionals. Always consult a licensed healthcare provider for medical advice and prescribing decisions. GNH USA supplies this product subject to applicable regulatory and licensing requirements.

Product details

Drug
Chlormadinone Acetate, Ethinylestradiol
Route
Oral Use
Manufacturer
Aristo Pharma Gmbh (Art 57)
Origin
EU

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