Lidonostrum

Lidocaine Hydrochloride, the active ingredient in Lidonostrum, is a local anesthetic presented as a formulation for buccal and gingival use. It provides local anesthesia of the oral mucosa and pain relief during dental procedures.

GNH USA supplies Lidonostrum as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Lidonostrum is a local anesthetic that acts on the oral mucosal nerves to provide temporary loss of sensation.

- Oral mucosal anesthesia: numbs the oral mucosa for minor surgical or diagnostic procedures. - Dental extraction pain relief: reduces pain during tooth removal. - Periodontal therapy: facilitates comfort during gingival manipulation and scaling.

Adverse reactions may occur following buccal or gingival application of lidocaine.

Common Side Effects: - Mild burning or stinging sensation at the application site. - Transient numbness lasting longer than the intended procedure. - Altered taste perception. - Localized swelling or mild irritation. - Redness of the mucosa.

Serious or Rare Side Effects: - Allergic reaction such as rash, urticaria, or angioedema. - Cardiac arrhythmias including ventricular tachycardia. - Central nervous system toxicity manifesting as seizures. - Severe hypotension. - Methemoglobinemia (very rare).

Before using Lidonostrum, consider the following safety measures.

- Allergy assessment: verify no known hypersensitivity to amide‑type local anesthetics. - Cardiac history: use with caution in patients with conduction disorders or arrhythmias. - Concomitant drugs: review medications that may lower seizure threshold. - Pregnancy and lactation: prescribe only if the anticipated benefit justifies potential risk. - Store below 25°C: keep in the original container, protect from moisture and light.

Lidonostrum may interact with other medicines; monitor patients accordingly.

Major Interactions (Avoid): - Class I antiarrhythmics (e.g., quinidine): increased risk of systemic toxicity. - Beta‑blockers (e.g., propranolol): may potentiate cardiotoxic effects.

Moderate Interactions (Monitor Closely): - Monoamine oxidase inhibitors: possible enhancement of central nervous system effects. - Tricyclic antidepressants: may raise seizure risk. - Alcohol: can augment local anesthetic toxicity.