GNH USA

Europe — EMA

Lidokain/Adrenalin Aguettant (Epinephrine, Lidocaine Hydrochloride)

GNH USA supplies Lidokain/Adrenalin Aguettant (Lidocaine/Epinephrine), a local anesthetic combination for surgical anesthesia, epidural analgesia and Bier

Epinephrine, Lidocaine Hydrochloride

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What is Epinephrine, Lidocaine Hydrochloride?

Lidocaine hydrochloride, the active ingredient in Lidokain/Adrenalin Aguettant, is a local anesthetic presented as a sterile solution for injection use. It provides local anesthesia for surgical or diagnostic procedures in adult patients. Epinephrine is included to prolong the anesthetic effect and reduce systemic absorption.

GNH USA supplies Lidokain/Adrenalin Aguettant as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, transplant centres, oncology centres, pharmacies and clinics worldwide.

What is Epinephrine, Lidocaine Hydrochloride used for?

Lidokain/Adrenalin Aguettant is a local anesthetic combination used in procedures requiring regional or infiltration anesthesia.

- Surgical procedures: provides rapid onset local anesthesia with prolonged duration for incision and excision. - Epidural analgesia: enables effective pain control during labor, obstetric or postoperative management. - Intravenous regional anesthesia (Bier block): allows safe, reversible anesthesia of a limb for short surgical interventions.

What are the side effects of Epinephrine, Lidocaine Hydrochloride?

Lidokain/Adrenalin Aguettant may cause a range of adverse reactions.

Common Side Effects: - Transient pain or burning at the injection site. - Tachycardia or increased heart rate. - Elevated blood pressure (hypertension). - Nausea or mild dizziness. - Localized swelling or erythema.

Serious or Rare Side Effects: - Severe allergic reaction (anaphylaxis) with airway compromise. - Cardiac arrhythmias, including ventricular tachycardia. - Seizures or central nervous system toxicity. - Methemoglobinemia. - Prolonged numbness or motor block beyond expected duration.

What precautions apply to Epinephrine, Lidocaine Hydrochloride?

Before using Lidokain/Adrenalin Aguettant, consider the following safety measures.

- Assess cardiovascular status: evaluate heart rate and blood pressure prior to administration. - Avoid in patients with known hypersensitivity to lidocaine or epinephrine: discontinue use if reaction occurs. - Use caution in hyperthyroid patients: monitor for tachyarrhythmia. - Limit total dose: adhere to recommended maximum dose based on patient weight and procedure. - Store at room temperature: keep in original container, protect from light and moisture.

What does Epinephrine, Lidocaine Hydrochloride interact with?

Lidokain/Adrenalin Aguettant can interact with several drug classes.

Major Interactions (Avoid): - Beta‑blockers: may potentiate bradycardia and hypotension. - Monoamine oxidase inhibitors (MAOIs): increase risk of hypertensive crisis. - Tricyclic antidepressants: may enhance cardiotoxic effects of lidocaine.

Moderate Interactions (Monitor Closely): - Other local anesthetics: risk of cumulative systemic toxicity. - Diuretics: may raise plasma lidocaine concentrations. - CYP3A4 inhibitors: may modestly increase lidocaine levels.

Frequently asked questions

What is Lidokain/Adrenalin Aguettant used for?+
Lidokain/Adrenalin Aguettant is a sterile injectable solution that combines lidocaine and epinephrine to provide local or regional anesthesia. It is commonly employed for surgical incision anesthesia, epidural analgesia during labor or postoperative care, and intravenous regional anesthesia (Bier block) for limb surgeries.
How does lidocaine work in this product?+
Lidocaine blocks voltage‑gated sodium channels on nerve membranes, preventing the initiation and propagation of action potentials. This interruption of nerve signaling results in loss of sensation in the targeted area, producing rapid and effective local anesthesia.
What is the usual dose of Lidokain/Adrenalin Aguettant?+
The specific dose and concentration are determined by the prescribing clinician based on the type of procedure, patient weight, and clinical guidelines. Healthcare professionals calculate the appropriate volume to achieve effective anesthesia while staying within safe maximum dose limits.
Is Lidokain/Adrenalin Aguettant safe during pregnancy or breastfeeding?+
Safety data for use in pregnancy and lactation are limited, and the product is classified as pregnancy category unknown. It should only be used if the potential benefit justifies the potential risk to the fetus or infant, and the decision should be made by a qualified healthcare provider.
How do I order Lidokain/Adrenalin Aguettant from GNH USA?+
To place an order, submit an enquiry on the product page at gnh-usa.com, specifying the required quantity. GNH USA works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including cold‑chain if needed), and import documentation.
How does this product compare with other local anesthetic options?+
Lidokain/Adrenalin Aguettant combines a fast‑acting amide anesthetic (lidocaine) with a vasoconstrictor (epinephrine), offering longer duration and reduced systemic absorption compared with lidocaine alone. Compared with bupivacaine, it has a quicker onset but a shorter duration, making it suitable for shorter procedures.
What are the storage and handling requirements for this product?+
The solution should be stored at room temperature, below 25 °C, in its original sealed container. Protect it from direct sunlight, moisture, and freezing. Do not use if the solution appears discolored or contains particles.
How is Lidokain/Adrenalin Aguettant administered?+
The product is administered by a qualified healthcare professional via injection. Routes include infiltration into tissue, epidural space, or intravenous regional (Bier) block. Proper aseptic technique and dosage calculation are essential for safe administration.
What are the most serious risks associated with this medication?+
Serious risks include severe allergic reactions (anaphylaxis), cardiac arrhythmias such as ventricular tachycardia, central nervous system toxicity leading to seizures, and methemoglobinemia. Immediate medical attention is required if any of these events occur.
Who should not use Lidokain/Adrenalin Aguettant?+
Patients with known hypersensitivity to lidocaine, epinephrine, or any component of the formulation should avoid this product. It is also contraindicated in individuals with uncontrolled severe hypertension, certain cardiac conduction disorders, or those taking non‑selective MAO inhibitors.
Information provided on this page is for educational use by procurement and clinical professionals. Always consult a licensed healthcare provider for medical advice and prescribing decisions. GNH USA supplies this product subject to applicable regulatory and licensing requirements.
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Product details

Drug
Epinephrine, Lidocaine Hydrochloride
Route
Epidural Use , Infiltration , Intravenous Use , Pe
Manufacturer
Laboratoire Aguettant
Origin
EU

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