GNH USA

Europe — EMA

Lidocaine With Adrenaline (Epinephrine) 1:200 000 Laboratoire Aguettant (Epinephrine, Lidocaine Hydrochloride)

GNH USA supplies Lidocaine With Adrenaline (Epinephrine), a local anesthetic for minor surgical, dental and epidural procedures. Request a quote globally.

Epinephrine, Lidocaine Hydrochloride

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What is Epinephrine, Lidocaine Hydrochloride?

Lidocaine, the active ingredient in Lidocaine With Adrenaline (Epinephrine) 1:200 000 Laboratoire Aguettant, is a local anesthetic presented as a sterile solution for injection for epidural, infiltration, intravenous and perineural use. It provides rapid onset numbness and, together with epinephrine, prolongs the anesthetic effect while reducing bleeding. GNH USA supplies Lidocaine With Adrenaline (Epinephrine) 1:200 000 Laboratoire Aguettant as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

What is Epinephrine, Lidocaine Hydrochloride used for?

Lidocaine combined with epinephrine is used in the local anesthetic pathway for minor surgical and dental procedures. - Minor surgical procedures: provides rapid onset anesthesia with prolonged duration and reduced intra‑operative bleeding. - Dental procedures: enables effective numbing of oral tissues while minimizing hemorrhage. - Epidural analgesia: offers segmental pain relief during labor or surgery. - Infiltration anesthesia: allows targeted anesthesia of specific tissue planes. - Perineural nerve blocks: facilitates prolonged nerve block for postoperative analgesia.

What are the side effects of Epinephrine, Lidocaine Hydrochloride?

Adverse reactions may occur following administration of lidocaine with epinephrine.

Common Side Effects: - Tingling or numbness at the injection site - Transient increase in heart rate - Mild hypertension - Local swelling or erythema

Serious or Rare Side Effects: - Severe allergic reaction (anaphylaxis) - Cardiac arrhythmia - Seizures - Methemoglobinemia (rare)

What precautions apply to Epinephrine, Lidocaine Hydrochloride?

When using lidocaine with epinephrine, consider the following safety measures. - Assess patient allergy: confirm no known hypersensitivity to lidocaine or epinephrine. - Monitor cardiovascular status: watch for tachycardia or hypertension during and after injection. - Use caution in patients with thyroid disease: epinephrine may exacerbate symptoms. - Avoid high doses in infants and the elderly: adjust based on weight and comorbidities. - Store at room temperature: keep in the original container, protect from light and moisture.

What does Epinephrine, Lidocaine Hydrochloride interact with?

Lidocaine with epinephrine can interact with several drug classes.

Major Interactions (Avoid): - MAO inhibitors: risk of hypertensive crisis with epinephrine. - Beta‑blockers: may blunt epinephrine's cardiovascular effects and cause severe hypertension. - Class I antiarrhythmics (e.g., quinidine): increase lidocaine toxicity. - Tricyclic antidepressants: additive central nervous system toxicity. - Non‑selective sympathomimetics: enhanced vasoconstriction.

Moderate Interactions (Monitor Closely): - Calcium channel blockers: may potentiate cardiac effects. - Diuretics: alter plasma concentration of lidocaine. - CYP3A4 inhibitors: may increase lidocaine levels.

Frequently asked questions

What is Lidocaine With Adrenaline (Epinephrine) used for?+
Lidocaine with epinephrine is employed as a local anesthetic for minor surgical, dental, epidural, infiltration and perineural nerve block procedures. The combination provides rapid numbness while the epinephrine component prolongs the effect and reduces bleeding at the site.
How does lidocaine work in this product?+
Lidocaine blocks voltage‑gated sodium channels on nerve cells, stopping the transmission of pain signals. Epinephrine activates alpha‑adrenergic receptors causing vasoconstriction, which limits systemic absorption of lidocaine, extends its duration, and minimizes local bleeding.
What is the usual dose of this medication?+
The dose of lidocaine with epinephrine is determined by the prescribing clinician based on the specific procedure, patient weight, age, and clinical condition. Only a qualified health professional should set the appropriate dosage and administration schedule.
Is this product safe to use during pregnancy or breastfeeding?+
Safety data for lidocaine with epinephrine in pregnancy and lactation are limited. The medication should only be used if the potential benefit justifies any possible risk to the fetus or infant, and it must be prescribed by a qualified health professional.
How do I order Lidocaine With Adrenaline (Epinephrine) from GNH USA?+
To place an order, submit an enquiry on the product page at gnh-usa.com, specifying the required quantity. GNH USA supplies hospitals, pharmacies and procurement teams worldwide, and will request trade or institutional credentials before providing pricing, availability, shipping details and any required import documentation.
How does this product compare with other local anesthetics?+
Compared with plain lidocaine, the addition of epinephrine offers longer duration of anesthesia and reduced intra‑operative bleeding due to vasoconstriction. It may be preferred over other agents when prolonged effect and hemostasis are desired, though the choice depends on the clinical scenario and patient factors.
What are the storage and handling requirements?+
Store the sterile solution at room temperature, preferably below 25 °C. Keep the vial in its original packaging, protect it from direct light and moisture, and ensure the container is sealed when not in use to maintain sterility.
How is the medication administered?+
Lidocaine with epinephrine is administered by a qualified health professional via injection. Routes include epidural, infiltration, intravenous or perineural techniques, depending on the intended anesthetic effect and the specific procedure being performed.
What are the most serious risks associated with this drug?+
Serious risks include severe allergic reactions (anaphylaxis), cardiac arrhythmias, seizures, and rare cases of methemoglobinemia. Immediate medical attention is required if any of these events occur during or after administration.
Who should not use this medication?+
Patients with known hypersensitivity to lidocaine, epinephrine, or any component of the formulation should avoid this product. Caution is also advised for individuals with severe cardiac disease, uncontrolled hypertension, hyperthyroidism, or certain metabolic disorders, and the decision should be made by a healthcare professional.
Information provided on this page is for educational use by procurement and clinical professionals. Always consult a licensed healthcare provider for medical advice and prescribing decisions. GNH USA supplies this product subject to applicable regulatory and licensing requirements.
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Product details

Drug
Epinephrine, Lidocaine Hydrochloride
Route
Epidural Use , Infiltration , Intravenous Use , Pe
Manufacturer
Laboratoire Aguettant
Origin
EU

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