Lidocaïne/Prilocaïne Biogaran

Lidocaine, the active ingredient in Lidocaïne/Prilocaïne Biogaran, is a local anesthetic presented as a topical formulation for surface anesthesia. It provides reversible nerve block for minor skin procedures, venipuncture and other superficial interventions. GNH USA supplies Lidocaïne/Prilocaïne Biogaran as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Lidocaine/Prilocaine is a topical local anesthetic used to achieve surface numbness for minor procedures.

Minor skin procedures: provides temporary loss of sensation for biopsies, laser therapy or minor excisions. Venipuncture and cannulation: reduces pain during blood draws and intravenous line placement. Dermatologic procedures: facilitates cosmetic or therapeutic skin treatments such as dermabrasion or chemical peels.

Lidocaine/Prilocaine may cause local and systemic adverse reactions.

Common Side Effects: - Mild skin irritation at the application site. - Transient erythema or redness. - Pruritus or itching where applied. - Slight burning sensation during initial application. - Dryness or peeling of the skin.

Serious or Rare Side Effects: - Allergic contact dermatitis with swelling or vesicles. - Systemic toxicity presenting as dizziness, tinnitus, or seizures. - Methemoglobinemia, a rare blood disorder causing cyanosis. - Cardiac arrhythmias in cases of excessive absorption. - Severe hypotension or respiratory depression.

Before using Lidocaine/Prilocaine, consider the following safety measures. - Allergy assessment: confirm no known hypersensitivity to amide‑type local anesthetics. - Application area: avoid use on large surface areas, broken skin, or mucous membranes. - Age considerations: use with caution in neonates, infants, and the elderly. - Concurrent medications: be aware of agents that may increase systemic absorption or toxicity. - Pregnancy and lactation: safety not established; weigh benefits against potential risks. - Store at room temperature: keep in the original container, protect from moisture and direct sunlight.

Lidocaine/Prilocaine can interact with other medicines, affecting safety and efficacy.

Major Interactions (Avoid): - Class I antiarrhythmics (e.g., quinidine, procainamide): may increase systemic toxicity. - Beta‑blockers (e.g., propranolol): can potentiate cardiac effects.

Moderate Interactions (Monitor Closely): - Other local anesthetics: cumulative dose may raise toxicity risk. - Monoamine oxidase inhibitors: may alter metabolism of lidocaine. - CYP2D6 inhibitors: could reduce clearance of lidocaine, increasing plasma levels.