GNH USA

Europe — EMA

Lidina

GNH USA supplies Lidina (Ketotifen Hydrogen Fumarate), a antiallergic ophthalmic agent for allergic conjunctivitis and seasonal allergic eye disease.

Ketotifen Hydrogen Fumarate

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What is Ketotifen Hydrogen Fumarate?

Ketotifen hydrogen fumarate, the active ingredient in Lidina, is an antihistamine (H1 receptor antagonist) and mast cell stabilizer presented as an ophthalmic solution for ocular use. It is employed to relieve eye allergy symptoms such as itching, redness, and swelling in patients with allergic conjunctivitis or seasonal allergic eye disease.

GNH USA supplies Lidina as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

What is Ketotifen Hydrogen Fumarate used for?

Lidina, an antiallergic ophthalmic agent, is indicated for ocular allergic conditions affecting the conjunctiva and cornea.

Allergic conjunctivitis: reduces itching, redness, and swelling of the eye surface. Seasonal allergic eye disease: alleviates symptoms triggered by seasonal allergens such as pollen. Allergic keratoconjunctivitis: helps control inflammation of both the cornea and conjunctiva, improving comfort and visual clarity.

What are the side effects of Ketotifen Hydrogen Fumarate?

Lidina may cause ocular and systemic adverse reactions, which are categorized by frequency and severity.

Common Side Effects: - Eye irritation or burning sensation: transient discomfort after instillation. - Stinging or itching: mild sensation that usually resolves quickly. - Blurred vision: temporary visual disturbance lasting minutes. - Dry eye sensation: mild dryness of the ocular surface.

Serious or Rare Side Effects: - Severe allergic reaction (anaphylaxis): rare but requires immediate medical attention. - Corneal ulcer or keratitis: persistent pain, redness, and vision changes. - Significant visual loss: sudden decrease in vision warrants urgent evaluation.

What precautions apply to Ketotifen Hydrogen Fumarate?

Before using Lidina, consider the following precautions to ensure safe and effective therapy.

Pregnancy: safety has not been established; consult a healthcare professional before use. Breastfeeding: unknown effect on the infant; weigh potential benefits against risks. Contact lens wearers: may experience increased discomfort; remove lenses before instillation and wait before reinserting. Concurrent ocular infections: use with caution as symptoms may be masked; monitor closely. Store below 25°C: keep in the original container, protect from light and moisture.

What does Ketotifen Hydrogen Fumarate interact with?

Lidina can interact with other ophthalmic or systemic agents; awareness of these interactions helps avoid adverse outcomes.

Major Interactions (Avoid): - Other topical antihistamines: additive ocular irritation may occur. - Systemic antihistamines: combined use can increase sedation or systemic antihistaminic effects.

Moderate Interactions (Monitor Closely): - Beta‑blocker eye drops: may enhance ocular hypotensive effects, requiring monitoring of intra‑ocular pressure. - Non‑steroidal anti‑inflammatory eye drops: possible reduction in anti‑inflammatory efficacy. - Anticholinergic eye drops: may increase ocular dryness when used together.

Frequently asked questions

What is Lidina used for?+
Lidina is an ophthalmic preparation containing ketotifen hydrogen fumarate. It is used to treat allergic eye conditions such as allergic conjunctivitis and seasonal allergic eye disease by relieving symptoms like itching, redness, and swelling.
How does ketotifen hydrogen fumarate work?+
Ketotifen hydrogen fumarate works by blocking H1 histamine receptors on the eye surface, preventing histamine‑induced itching and vasodilation. At the same time it stabilises mast cells, reducing the release of inflammatory mediators that contribute to ocular allergy symptoms.
What is the usual dose of Lidina?+
The dosing regimen for Lidina is determined by the prescribing clinician based on the severity of the allergic eye condition and patient response. Typically, one or two drops are instilled in the affected eye(s) as directed, but the exact schedule should follow the healthcare professional’s instructions.
Is Lidina safe during pregnancy or breastfeeding?+
Safety data for ketotifen hydrogen fumarate in pregnancy and lactation are limited. The product should be used only if the potential benefit justifies any possible risk to the fetus or infant, and this decision should be made in consultation with a qualified healthcare provider.
How do I order Lidina from GNH USA?+
To order Lidina, submit an enquiry on the product page at gnh-usa.com, specifying the required quantity. GNH USA works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including any cold‑chain requirements) and necessary import documentation.
How does Lidina compare with other antiallergic eye drops?+
Lidina combines antihistamine activity with mast‑cell stabilisation, offering both immediate symptom relief and longer‑term control of inflammation. Some other eye drops provide only antihistamine effects, while corticosteroid drops give strong anti‑inflammatory action but carry higher risk of side effects. Lidina therefore occupies a middle ground with a favourable safety profile for routine allergic eye disease.
How should Lidina be stored and handled?+
Lidina should be stored below 25 °C in its original packaging, protected from light and moisture. Keep the bottle tightly closed when not in use, and avoid freezing. If the product appears discoloured or the container is damaged, discard it and obtain a new supply.
How is Lidina administered?+
Lidina is applied topically to the eye. After washing hands, tilt the head back, pull down the lower eyelid to create a small pocket, and instil the prescribed number of drops into the conjunctival sac. Close the eye gently for a few seconds and avoid blinking excessively. Do not touch the dropper tip to any surface.
What are the most serious risks to watch for when using Lidina?+
Although uncommon, serious adverse events can include severe allergic reactions such as anaphylaxis, corneal ulcer or keratitis, and sudden loss of vision. If any of these occur, discontinue the product immediately and seek urgent medical attention.
Who should not use Lidina?+
Lidina should be avoided in individuals with known hypersensitivity to ketotifen or any excipients in the formulation. Patients with active ocular infections or severe ocular surface disease should consult an eye‑care professional before use, as the medication may mask symptoms or exacerbate the condition.
Information provided on this page is for educational use by procurement and clinical professionals. Always consult a licensed healthcare provider for medical advice and prescribing decisions. GNH USA supplies this product subject to applicable regulatory and licensing requirements.

Product details

Drug
Ketotifen Hydrogen Fumarate
Route
Ocular Use
Manufacturer
Laboratório Edol - Produtos Farmacêuticos, S.A.
Origin
EU

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