Liaflox

Ofloxacin, the active ingredient in Liaflox, is a fluoroquinolone antibiotic presented as an ophthalmic solution for ocular use. It treats bacterial infections of the eye, such as conjunctivitis and keratitis, in adult and pediatric patients as prescribed by a qualified clinician.

GNH USA supplies Liaflox as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide. The company adheres to EU quality standards and provides regulatory documentation for importers. Its global logistics network ensures timely delivery to diverse healthcare settings.

Ofloxacin ophthalmic solution is indicated for bacterial eye infections, targeting the ocular surface and corneal tissues.

- Bacterial conjunctivitis: reduces bacterial load and accelerates resolution of redness, discharge, and irritation. - Bacterial keratitis: eradicates causative organisms and promotes healing of corneal ulcers. - Other ocular bacterial infections: treats infection of the eyelid margin, lacrimal sac, or postoperative ocular sites.

Ophthalmic ofloxacin may cause local and systemic adverse reactions, most of which are mild and transient.

Common Side Effects: - Stinging or burning on instillation. - Temporary blurred vision. - Redness of the conjunctiva.

Serious or Rare Side Effects: - Corneal ulceration or perforation. - Severe allergic reaction (e.g., angioedema, anaphylaxis). - Tendon rupture or systemic tendonitis.

When prescribing ophthalmic ofloxacin, clinicians should consider several precautionary measures to minimize risk. - Assess patient history: exclude known hypersensitivity to fluoroquinolones. - Use with caution in patients with corneal epithelial defects. - Avoid concomitant use with other topical ocular antibiotics unless directed. - Monitor for signs of tendon pain or systemic fluoroquinolone reactions. - Advise patients to report severe eye pain, vision changes, or allergic symptoms promptly. - Store below 25°C: keep in original container, protect from light and moisture.

Ofloxacin ophthalmic solution can interact with other medicines, affecting its safety or efficacy.

Major Interactions (Avoid): - Systemic fluoroquinolones: concurrent use may increase risk of tendon toxicity. - Anticholinergic eye drops (e.g., atropine): may reduce ocular absorption.

Moderate Interactions (Monitor Closely): - Non‑steroidal anti‑inflammatory eye drops: may increase risk of corneal irritation. - Corticosteroid eye preparations: may mask signs of infection. - Oral antacids containing magnesium or aluminum: can affect systemic absorption if oral fluoroquinolone is also used.