GNH USA

Europe — EMA

Lexavon

GNH USA supplies Lexavon (Levofloxacin), a fluoroquinolone antibiotic for bacterial conjunctivitis, keratitis and blepharitis. Request a quote for supply.

Levofloxacin Hemihydrate

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What is Levofloxacin Hemihydrate?

Levofloxacin, the active ingredient in Lexavon, is a fluoroquinolone antibiotic presented as an ophthalmic solution for ocular use. It treats bacterial infections of the eye such as conjunctivitis, keratitis and blepharitis in patients requiring prescription therapy.

GNH USA supplies Lexavon as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

What is Levofloxacin Hemihydrate used for?

Lexavon, a fluoroquinolone ophthalmic antibiotic, is indicated for bacterial infections of the ocular surface.

- Bacterial conjunctivitis: reduces bacterial load and promotes resolution of conjunctival infection. - Bacterial keratitis: eradicates pathogenic bacteria to prevent corneal damage. - Blepharitis: controls bacterial overgrowth on the eyelid margin, improving inflammation and symptoms.

What are the side effects of Levofloxacin Hemihydrate?

Adverse reactions may occur with ocular administration of Lexavon.

Common Side Effects: - Eye irritation: transient burning or stinging sensation. - Redness: mild conjunctival hyperemia. - Foreign body sensation: feeling of grit in the eye. - Blurred vision: temporary visual disturbance. - Tearing: increased lacrimation. - Photophobia: sensitivity to light.

Serious or Rare Side Effects: - Corneal ulceration: progressive corneal damage requiring immediate attention. - Allergic reaction: swelling, rash, or severe itching of the eye. - Stevens‑Johnson syndrome: rare systemic hypersensitivity with mucosal involvement. - Severe ocular inflammation: marked swelling or pain indicating possible infection progression.

What precautions apply to Levofloxacin Hemihydrate?

Lexavon should be used with caution and according to professional guidance.

- Hypersensitivity: avoid in patients with known allergy to fluoroquinolones. - Contact lenses: do not wear lenses during treatment unless advised. - Infection monitoring: discontinue if condition worsens or new symptoms appear. - Prescription use: follow the prescriber's instructions precisely. - Storage: Store at room temperature: keep in original container, protect from light and moisture.

What does Levofloxacin Hemihydrate interact with?

Lexavon may interact with other ocular or systemic agents.

Major Interactions (Avoid): - Systemic fluoroquinolones: increased risk of tendon toxicity. - Corticosteroid eye drops: may mask signs of infection. - Live vaccines: potential reduction in vaccine efficacy.

Moderate Interactions (Monitor Closely): - Anticholinergic eye drops: possible pupil size alteration. - NSAID eye drops: additive ocular irritation. - Warfarin: may enhance anticoagulant effect, requiring INR monitoring.

Frequently asked questions

What is Lexavon used for?+
Lexavon is a prescription ophthalmic solution containing levofloxacin, a fluoroquinolone antibiotic. It is used to treat bacterial infections of the eye, specifically bacterial conjunctivitis, bacterial keratitis, and blepharitis, by eliminating the causative microorganisms and helping to restore ocular health.
How does levofloxacin work?+
Levofloxacin works by binding to bacterial DNA gyrase and topoisomerase IV, enzymes that are essential for DNA replication and transcription. Inhibiting these enzymes stops bacterial cell division, leading to bacterial death and clearance of the infection in the treated eye.
What is the usual dose of Lexavon?+
The dosage and frequency of Lexavon are determined by the prescribing clinician based on the specific infection, severity, and patient factors. The prescriber will provide detailed instructions on how many drops to instill and how often they should be applied.
Is Lexavon safe in pregnancy or breastfeeding?+
Safety of levofloxacin ophthalmic use during pregnancy or lactation has not been definitively established. It should only be used if the potential benefit justifies any possible risk to the fetus or infant, and this decision must be made by the treating physician.
How do I order Lexavon from GNH USA?+
To order Lexavon, submit an enquiry on the product page at gnh-usa.com, specifying the required quantity. GNH USA works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.
How does Lexavon compare with other ocular antibiotics?+
Lexavon (levofloxacin) offers broad‑spectrum coverage against Gram‑positive and Gram‑negative ocular pathogens and has a favorable penetration profile in corneal tissue. Compared with older agents such as ciprofloxacin, levofloxacin often requires fewer daily administrations and may have a lower risk of resistance development.
How should Lexavon be stored and handled?+
Lexavon should be stored at room temperature, away from direct sunlight and moisture. Keep the bottle tightly closed when not in use and retain it in its original packaging to protect the solution from contamination.
How is Lexavon administered?+
Lexavon is applied as eye drops directly onto the affected eye(s) according to the prescriber's directions. Typically, the patient tilts the head back, pulls down the lower eyelid to create a pocket, instills the prescribed number of drops, and gently closes the eye for a few seconds. Contact lenses should be removed unless otherwise instructed.
What are the most serious risks to watch for when using Lexavon?+
Serious adverse events, although rare, include corneal ulceration, severe allergic reactions such as swelling or rash, and systemic hypersensitivity syndromes like Stevens‑Johnson syndrome. Patients should seek immediate medical attention if they experience worsening pain, vision changes, or signs of a severe reaction.
Who should not use Lexavon?+
Lexavon should not be used by individuals with a known hypersensitivity to levofloxacin, other fluoroquinolones, or any component of the formulation. It is also contraindicated in patients with active viral or fungal eye infections, as the drug does not treat these conditions.
Information provided on this page is for educational use by procurement and clinical professionals. Always consult a licensed healthcare provider for medical advice and prescribing decisions. GNH USA supplies this product subject to applicable regulatory and licensing requirements.

Product details

Drug
Levofloxacin Hemihydrate
Route
Ocular Use
Manufacturer
Rafarm Sa.
Origin
EU

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