Lexavon

Levofloxacin, the active ingredient in Lexavon, is a fluoroquinolone antibiotic presented as an ophthalmic solution for ocular use. It treats bacterial eye infections such as conjunctivitis, keratitis and post‑operative infections in adults and children.

GNH USA supplies Lexavon as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Levofloxacin ophthalmic drops act on bacterial pathogens that cause eye infections. They are indicated for: - Bacterial conjunctivitis: reduces redness, discharge and bacterial load in the conjunctiva. - Bacterial keratitis: eradicates causative organisms and promotes corneal healing. - Post‑operative ocular infection: prevents or treats infection after eye surgery, supporting recovery.

Levofloxacin ophthalmic solution may cause local and systemic adverse reactions.

Common Side Effects: - Ocular irritation: mild burning or stinging on instillation. - Redness: transient conjunctival hyperemia. - Tearing: increased lacrimation. - Blurred vision: temporary visual disturbance. - Foreign body sensation: feeling of grit in the eye. - Mild headache: occasional peri‑ocular discomfort.

Serious or Rare Side Effects: - Allergic reaction: swelling, rash or hives around the eye. - Stevens‑Johnson syndrome: severe mucocutaneous blistering. - Corneal ulceration: worsening of corneal lesions. - Severe eye pain: persistent or worsening discomfort. - Vision loss: sudden decrease in visual acuity. - Systemic hypersensitivity: fever, chills or joint pain.

Levofloxacin ophthalmic drops require careful use to minimise risks. - Allergy assessment: confirm no known hypersensitivity to fluoroquinolones. - Age considerations: use with caution in pediatric patients; safety data are limited. - Contact lens wearers: avoid lens use until treatment is completed and the eye is clear. - Systemic absorption: monitor for systemic fluoroquinolone effects during prolonged therapy. - Pregnancy and lactation: safety not established; avoid unless benefit outweighs risk. - Store at room temperature: keep in the original container, protect from light and moisture.

Levofloxacin ophthalmic solution can interact with other ocular or systemic agents.

Major Interactions (Avoid): - Systemic fluoroquinolones: concurrent use may increase risk of tendon rupture. - Corticosteroid eye drops: may reduce antimicrobial efficacy and delay healing. - Anticholinergic agents: may exacerbate ocular dryness.

Moderate Interactions (Monitor Closely): - Non‑steroidal anti‑inflammatory eye drops: monitor for delayed corneal healing. - Herbal supplements containing quinine: may increase systemic exposure. - High‑dose vitamin C: may affect ocular drug absorption.