GNH USA

Europe — EMA

Levopraid

GNH USA supplies Levopraid (Levosulpiride), an antipsychotic for schizophrenia, depressive disorders and functional dyspepsia. Request a quote for supply.

Levosulpiride

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What is Levosulpiride?

Levosulpiride, the active ingredient in Levopraid, is a benzamide antipsychotic presented as an oral tablet for oral use. It is employed in the management of schizophrenia, depressive disorders, functional dyspepsia and gastroparesis in adult patients. GNH USA supplies Levopraid as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

What is Levosulpiride used for?

Levosulpiride acts on dopaminergic pathways and gastrointestinal motility, making it useful in several psychiatric and gastro‑pro‑kinetic indications.

Schizophrenia: reduces psychotic symptoms and improves overall mental stability. Depressive disorders: alleviates depressive symptoms when used as an adjunct therapy. Functional dyspepsia and gastroparesis: enhances gastric emptying and relieves dyspeptic discomfort.

What are the side effects of Levosulpiride?

Levosulpiride may cause a range of adverse reactions, varying from mild to severe.

Common Side Effects: - Nausea - Dizziness - Headache - Dry mouth - Constipation - Somnolence

Serious or Rare Side Effects: - Extrapyramidal symptoms (e.g., akathisia, dystonia) - Hyperprolactinemia - Severe allergic reactions (e.g., rash, angioedema) - Cardiac arrhythmias - Neuroleptic malignant syndrome

What precautions apply to Levosulpiride?

When prescribing levosulpiride, clinicians should consider several safety measures.

Monitor for extrapyramidal symptoms: observe patients for movement disorders. Assess liver function: adjust use in hepatic impairment. Use caution in the elderly: increased sensitivity to side effects. Avoid abrupt discontinuation: taper to reduce withdrawal effects. Review concomitant medications: consider additive CNS depression. Store at room temperature: keep in the original pack, protect from moisture.

What does Levosulpiride interact with?

Levosulpiride can interact with other medicines, requiring careful management.

Major Interactions (Avoid): - MAO inhibitors: risk of hypertensive crisis. - Strong D2 antagonists (other antipsychotics): heightened extrapyramidal risk. - QT‑prolonging agents: potential cardiac arrhythmias.

Moderate Interactions (Monitor Closely): - CNS depressants (e.g., benzodiazepines): increased sedation. - Antihypertensives: possible additive blood pressure lowering. - Antidiabetic drugs: monitor glucose control. - SSRIs and other serotonergic agents: watch for serotonin syndrome. - Alcohol: may enhance central nervous system effects.

Frequently asked questions

What conditions is Levopraid used to treat?+
Levopraid, containing levosulpiride, is indicated for the treatment of schizophrenia and other psychotic disorders, depressive disorders as an adjunct, and functional dyspepsia or gastroparesis where it helps improve gastric motility.
How does levosulpiride work in the body?+
Levosulpiride works by selectively blocking dopamine D2 receptors in the brain, which reduces psychotic symptoms. In the gastrointestinal system, this blockade increases acetylcholine release, stimulating smooth‑muscle activity and promoting faster gastric emptying.
What is the usual dose of Levopraid?+
The dosage of Levopraid is individualized by the prescribing clinician based on the patient’s condition, severity, and response. The prescriber determines the appropriate strength, frequency, and duration of therapy.
Is Levopraid safe to use during pregnancy or breastfeeding?+
Safety data for levosulpiride in pregnancy and lactation are limited. It should only be used if the potential benefit justifies any potential risk to the fetus or infant, and the decision must be made by a qualified healthcare professional.
How do I order Levopraid from GNH USA?+
To place an order, submit an enquiry on the Levopraid product page at gnh-usa.com, specifying the required quantity. GNH USA works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.
How does Levopraid compare with other antipsychotic drugs?+
Levopraid (levosulpiride) is a benzamide antipsychotic that primarily blocks D2 receptors with additional pro‑kinetic effects, distinguishing it from many atypical antipsychotics that have broader receptor profiles. Its dual psychiatric and gastro‑pro‑kinetic activity can be advantageous in patients with co‑existing digestive symptoms.
What are the storage requirements for Levopraid?+
Levopraid tablets should be stored at room temperature, below 25 °C, in the original packaging to protect them from moisture and light. No refrigeration is required.
How is Levopraid administered?+
Levopraid is taken orally, usually with or without food, as directed by the prescribing physician. The tablets are swallowed whole with a glass of water.
What are the most serious risks associated with Levopraid?+
Serious risks include extrapyramidal symptoms such as dystonia or akathisia, hyperprolactinemia, severe allergic reactions, cardiac arrhythmias, and the rare but life‑threatening neuroleptic malignant syndrome. Patients should be monitored closely for these events.
Who should not use Levopraid?+
Levopraid is contraindicated in patients with known hypersensitivity to levosulpiride or any component of the formulation, and it should be used with caution in individuals with severe hepatic impairment, uncontrolled cardiac disease, or a history of neuroleptic malignant syndrome.
Information provided on this page is for educational use by procurement and clinical professionals. Always consult a licensed healthcare provider for medical advice and prescribing decisions. GNH USA supplies this product subject to applicable regulatory and licensing requirements.
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Product details

Drug
Levosulpiride
Route
Oral Use
Manufacturer
Teofarma S.R.L.
Origin
EU

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