Europe — EMA
Levonorgestrel/Etinilestradiol Pensa (Ethinylestradiol, Levonorgestrel)
GNH USA supplies Levonorgestrel/Etinilestradiol Pensa (Ethinylestradiol/Levonorgestrel), a combined estrogen‑progestogen oral contraceptive for pregnancy
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What is Ethinylestradiol, Levonorgestrel?
Ethinylestradiol, the active ingredient in Levonorgestrel/Etinilestradiol Pensa, is a combined estrogen‑progestogen oral contraceptive presented as an oral tablet for oral use. It works by suppressing ovulation and altering cervical mucus, providing reliable contraception when taken as prescribed.\n\nGNH India supplies Levonorgestrel/Etinilestradiol Pensa as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide, adhering to EU quality standards and providing reliable global distribution.
What is Ethinylestradiol, Levonorgestrel used for?
Levonorgestrel/Etinilestradiol Pensa, a combined estrogen‑progestogen oral contraceptive, is used in the hormonal regulation of the menstrual cycle to prevent pregnancy.\n\n- Pregnancy prevention: provides reliable contraception when taken daily as directed.\n- Menstrual cycle regulation: helps establish a predictable menstrual pattern and reduces cycle irregularities.\n- Dysmenorrhea relief: lessens menstrual pain associated with primary dysmenorrhea.\n- Acne management: improves mild to moderate acne by reducing androgenic activity.
What are the side effects of Ethinylestradiol, Levonorgestrel?
Levonorgestrel/Etinilestradiol Pensa may be associated with a range of adverse reactions, which are generally categorized by frequency and severity.\n\nCommon Side Effects:\n- Nausea: mild to moderate stomach upset.\n- Headache: tension‑type or migraine‑like pain.\n- Breast tenderness: swelling or discomfort of the breasts.\n- Spotting or breakthrough bleeding: irregular light bleeding between periods.\n- Weight change: slight increase or decrease in body weight.\n- Mood changes: irritability or emotional fluctuations.\n\nSerious or Rare Side Effects:\n- Venous thromboembolism: deep‑vein thrombosis or pulmonary embolism.\n- Stroke: ischemic or hemorrhagic cerebrovascular event.\n- Myocardial infarction: heart attack due to reduced coronary flow.\n- Severe hypertension: sudden, dangerous rise in blood pressure.\n- Liver tumor: benign hepatic adenoma in rare cases.\n- Allergic reaction: rash, swelling, or anaphylaxis.
What precautions apply to Ethinylestradiol, Levonorgestrel?
Before prescribing Levonorgestrel/Etinilestradiol Pensa, clinicians should consider several safety factors.\n- Contraindicated in women with a history of thromboembolic disorders: avoid use due to increased clot risk.\n- Avoid in smokers over 35 years: smoking adds cardiovascular risk.\n- Assess blood pressure before initiating therapy: monitor for hypertension.\n- Review liver function: hepatic disease may affect hormone metabolism.\n- Consider drug interactions with enzyme inducers: may reduce contraceptive efficacy.\n- Store at ambient temperature: keep below 25 °C, protect from moisture and light in the original packaging.
What does Ethinylestradiol, Levonorgestrel interact with?
Levonorgestrel/Etinilestradiol Pensa can interact with several medicines, influencing its effectiveness or safety.\n\nMajor Interactions (Avoid):\n- Enzyme‑inducing anticonvulsants (e.g., carbamazepine, phenytoin): may cause contraceptive failure.\n- Rifampin or rifabutin: reduces hormone levels, increasing risk of unintended pregnancy.\n- Protease inhibitors (e.g., ritonavir): can raise hormone concentrations, heightening side‑effect risk.\n\nModerate Interactions (Monitor Closely):\n- St. John’s wort: may lower contraceptive efficacy.\n- Certain antibiotics (e.g., griseofulvin): modestly reduce hormone levels.\n- Selective serotonin reuptake inhibitors: may increase incidence of mood changes.



