GNH USA

Europe — EMA

Levoftal

GNH USA supplies Levoftal (Levofloxacin), a fluoroquinolone antibacterial for ocular infections such as conjunctivitis and keratitis.

Levofloxacin Hemihydrate

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What is Levofloxacin Hemihydrate?

Levofloxacin, the active ingredient in Levoftal, is a fluoroquinolone presented as an ophthalmic solution for ocular use. The formulation is designed for topical application to the eye, delivering high local concentrations while minimizing systemic exposure. It is employed to treat bacterial eye infections in adults and children when prescribed by a qualified healthcare professional.

GNH USA supplies Levoftal as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide. The company adheres to European Union quality standards and provides regulatory‑approved batches to meet global demand.

What is Levofloxacin Hemihydrate used for?

Levoftal (levofloxacin) is a fluoroquinolone antibacterial indicated for bacterial infections of the eye.

- Bacterial conjunctivitis: reduces bacterial load, alleviating redness, discharge and discomfort. - Bacterial keratitis (corneal ulcer): eradicates causative organisms, promoting corneal healing and preventing scarring. - Blepharitis: eliminates bacterial colonisation of the eyelid margin, improving inflammation and crusting. - Post‑operative ocular prophylaxis: prevents bacterial infection after eye surgery.

What are the side effects of Levofloxacin Hemihydrate?

Levoftal may cause ocular and systemic adverse reactions, which are categorized by frequency and severity.

Common Side Effects: - Eye irritation or burning: mild discomfort that usually resolves within minutes after instillation. - Conjunctival redness: transient hyperemia of the eye surface. - Blurred vision: temporary visual disturbance that clears as the drop is absorbed. - Tearing (epiphora): increased lacrimal secretion shortly after dosing. - Photophobia: heightened sensitivity to light that diminishes with continued use. - Mild headache: occasional cephalic discomfort not directly related to ocular tissue.

Serious or Rare Side Effects: - Corneal ulceration or thinning: progressive loss of corneal tissue requiring immediate medical attention. - Severe allergic reaction: signs such as angioedema, swelling, or anaphylaxis demand urgent care.

What precautions apply to Levofloxacin Hemihydrate?

When using Levoftal, several precautions should be observed to ensure safety and effectiveness.

- Allergy assessment: confirm no known hypersensitivity to fluoroquinolones or levofloxacin before use. - Contact lens wear: advise removal of lenses before instillation and delay reinsertion until after dosing. - Pediatric use: limit to children for whom the benefit outweighs risk, as safety data are limited. - Concurrent ocular disease: use with caution in patients with pre‑existing corneal disorders. - Store at room temperature below 25°C: keep in original container, protect from moisture and light.

What does Levofloxacin Hemihydrate interact with?

Levoftal can interact with other ophthalmic or systemic agents; awareness of these interactions helps prevent adverse outcomes.

Major Interactions (Avoid): - Systemic fluoroquinolones: concurrent systemic use may increase risk of tendon rupture and central nervous system effects. - Corticosteroid eye drops: may potentiate risk of corneal perforation when combined.

Moderate Interactions (Monitor Closely): - Non‑steroidal anti‑inflammatory eye drops: monitor for delayed wound healing. - Anticholinergic agents: may reduce tear production, affecting drug distribution. - Herbal supplements containing quinine: potential additive QT prolongation, monitor cardiac status.

Frequently asked questions

What is Levoftal used for?+
Levoftal is a prescription ophthalmic solution containing levofloxacin, used to treat bacterial infections of the eye such as conjunctivitis, keratitis and blepharitis. It works by eliminating the causative bacteria, helping to reduce inflammation, discharge and visual discomfort.
How does levofloxacin work?+
Levofloxacin inhibits bacterial DNA gyrase and topoisomerase IV, enzymes required for DNA replication and transcription. By blocking these targets, the drug prevents bacterial cell division and leads to rapid bacterial cell death, providing a broad‑spectrum antibacterial effect in ocular tissues.
What is the usual dose of Levoftal?+
The dosing regimen for Levoftal is determined by the prescribing clinician based on the specific infection, severity and patient factors. The prescriber will specify the number of drops, frequency and duration of therapy on the prescription label.
Is Levoftal safe in pregnancy or breastfeeding?+
Safety data for levofloxacin ophthalmic use during pregnancy or lactation are limited. It should only be used if the potential benefit justifies any potential risk to the fetus or infant, and the decision should be made by a qualified healthcare professional.
How do I order Levoftal from GNH USA?+
To order Levoftal, submit an enquiry on the product page at gnh-usa.com, indicating the required quantity. GNH USA works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any required import documentation.
How does Levoftal compare with other ophthalmic antibiotics?+
Levoftal (levofloxacin) offers a broad spectrum against Gram‑negative and Gram‑positive bacteria and has good ocular tissue penetration. Compared with older agents such as ciprofloxacin, levofloxacin often requires fewer daily doses and may have a lower risk of resistance, though choice depends on local susceptibility patterns and clinician preference.
How should Levoftal be stored and handled?+
Levoftal should be stored at room temperature below 25 °C, in its original container, protected from moisture and direct light. Do not freeze the product. Keep the vial tightly closed when not in use and discard any solution that appears discolored or contaminated.
How is Levoftal administered?+
Levoftal is applied as eye drops. The prescribed number of drops is placed into the lower conjunctival sac of the affected eye(s) using a clean fingertip to pull down the lower eyelid. Avoid touching the dropper tip to the eye or any surface to maintain sterility.
What are the most serious risks associated with Levoftal?+
Serious adverse reactions, although rare, include corneal ulceration or thinning and severe allergic responses such as angioedema or anaphylaxis. Patients should seek immediate medical attention if they notice worsening eye pain, loss of vision, swelling of the eyelids or signs of a systemic allergic reaction.
Who should not use Levoftal?+
Levoftal should not be used by individuals with a known hypersensitivity to levofloxacin, other fluoroquinolones, or any component of the formulation. Caution is also advised for patients with a history of tendon disorders, uncontrolled epilepsy or those taking medications that may prolong the QT interval.
Information provided on this page is for educational use by procurement and clinical professionals. Always consult a licensed healthcare provider for medical advice and prescribing decisions. GNH USA supplies this product subject to applicable regulatory and licensing requirements.

Product details

Drug
Levofloxacin Hemihydrate
Route
Ocular Use
Manufacturer
Rafarm Sa.
Origin
EU

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