GNH USA

Europe — EMA

Levofloxacine Evolugen

GNH USA supplies Levofloxacine Evolugen (Levofloxacin), a fluoroquinolone antibiotic indicated for community‑acquired respiratory tract infections, urinary

Levofloxacin

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What is Levofloxacin?

Levofloxacin, the active ingredient in Levofloxacine Evolugen, is a fluoroquinolone presented as an oral tablet for systemic use. It treats a range of bacterial infections in adult patients, including respiratory, urinary and skin infections.

GNH USA supplies Levofloxacine Evolugen as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

What is Levofloxacin used for?

Levofloxacine Evolugen is a fluoroquinolone antibiotic that targets a broad spectrum of bacterial pathogens in several infection sites.

- Community‑acquired respiratory tract infections: eradicates the causative bacteria and resolves symptoms such as cough and fever. - Urinary tract infections: eliminates uropathogens and promotes rapid symptom relief. - Skin and soft tissue infections: clears bacterial involvement and aids wound healing. - Intra‑abdominal infections: provides coverage against common intra‑abdominal pathogens. - Gonorrhea: treats Neisseria gonorrhoeae infections resistant to other agents.

What are the side effects of Levofloxacin?

Levofloxacine Evolugen may cause a range of adverse reactions, most of which are mild and transient.

Common Side Effects: - Nausea - Diarrhea - Headache - Dizziness - Rash - Abdominal pain

Serious or Rare Side Effects: - Tendon rupture or tendinitis - QT‑interval prolongation and cardiac arrhythmias - Severe allergic reactions (anaphylaxis, Stevens‑Johnson syndrome) - Clostridioides difficile‑associated colitis - Peripheral neuropathy - Hepatic dysfunction

What precautions apply to Levofloxacin?

Before prescribing Levofloxacine Evolugen, clinicians should consider several safety aspects.

- Renal impairment: dose adjustment may be required based on renal function. - History of tendon disorders: avoid use in patients with prior tendon injury or those on corticosteroids. - Pregnancy Category C: use only when the potential benefit justifies the potential risk to the fetus. - Concomitant QT‑prolonging drugs: monitor electrocardiogram and electrolytes. - Known hypersensitivity to fluoroquinolones: contraindicated. - Store at room temperature: keep in the original container, protect from moisture and direct sunlight.

What does Levofloxacin interact with?

Levofloxacine Evolugen can interact with several medicines, altering efficacy or safety.

Major Interactions (Avoid): - Antacids or supplements containing magnesium, aluminum or calcium: reduce levofloxacin absorption. - Warfarin: may increase anticoagulant effect and bleeding risk. - Cyclosporine: increased cyclosporine concentrations may occur.

Moderate Interactions (Monitor Closely): - Non‑steroidal anti‑inflammatory drugs (NSAIDs): may increase risk of central nervous system stimulation. - Corticosteroids: combined use raises the chance of tendon rupture. - Other QT‑prolonging agents: monitor cardiac rhythm and electrolytes.

Frequently asked questions

What is Levofloxacine Evolugen used for?+
Levofloxacine Evolugen is a prescription‑only oral fluoroquinolone indicated for the treatment of community‑acquired respiratory tract infections, urinary tract infections, skin and soft‑tissue infections, intra‑abdominal infections and gonorrhea in adult patients.
How does levofloxacin work?+
Levofloxacin blocks bacterial DNA gyrase and topoisomerase IV, enzymes required for DNA replication and transcription. This inhibition prevents bacterial DNA from unwinding and resealing, leading to bacterial cell death and a bactericidal effect against susceptible organisms.
What is the usual dose of Levofloxacine Evolugen?+
The dosage of Levofloxacine Evolugen is determined by the prescribing clinician based on the infection type, severity, patient age, renal function and other clinical factors. No fixed regimen is provided here; the prescriber sets the appropriate dose.
Is Levofloxacine Evolugen safe during pregnancy or breastfeeding?+
Levofloxacine Evolugen is classified as Pregnancy Category C, meaning risk cannot be ruled out. It should be used only if the potential benefit to the mother outweighs any possible risk to the fetus. Caution is also advised during breastfeeding, and a healthcare professional should evaluate the risk‑benefit balance.
How do I order Levofloxacine Evolugen from GNH USA?+
To place an order, submit an enquiry on the product page at gnh-usa.com, specifying the required quantity. GNH USA works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including any cold‑chain requirements) and the necessary import documentation.
How does Levofloxacine Evolugen compare with other antibiotics?+
Compared with older fluoroquinolones, levofloxacin offers once‑daily dosing and a broader spectrum against Gram‑negative and some Gram‑positive pathogens. It is generally more potent than ciprofloxacin and has better lung penetration than many macrolides, making it a preferred option for certain respiratory infections, though safety considerations differ.
How should Levofloxacine Evolugen be stored and handled?+
Store the tablets at room temperature, below 25 °C, in the original blister pack or container. Protect them from moisture, excessive heat and direct sunlight. Do not refrigerate or freeze the product, and keep it out of reach of children.
How is Levofloxacine Evolugen given or administered?+
Levofloxacine Evolugen is taken orally with a full glass of water. It may be taken with or without food, but antacids or mineral supplements should be spaced at least two hours apart to avoid reduced absorption. Swallow the tablet whole; do not crush or chew.
What are the most serious risks to watch for while using Levofloxacine Evolugen?+
Serious adverse events include tendon rupture or tendinitis, especially in older adults or those on corticosteroids; QT‑interval prolongation leading to arrhythmias; severe allergic reactions such as anaphylaxis or Stevens‑Johnson syndrome; Clostridioides difficile‑associated colitis; peripheral neuropathy; and hepatic dysfunction. Prompt medical attention is required if any of these occur.
Who should not use Levofloxacine Evolugen?+
Levofloxacine Evolugen is contraindicated in patients with a known hypersensitivity to levofloxacin, other fluoroquinolones, or any component of the formulation. It should be avoided in children and adolescents unless no alternative therapy exists, and used with caution in pregnant or breastfeeding women, patients with a history of tendon disorders, and those with significant cardiac arrhythmias.
Information provided on this page is for educational use by procurement and clinical professionals. Always consult a licensed healthcare provider for medical advice and prescribing decisions. GNH USA supplies this product subject to applicable regulatory and licensing requirements.

Product details

Drug
Levofloxacin
Route
Oral Use
Manufacturer
Evolupharm
Origin
EU

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