GNH USA

Europe — EMA

Levofloxacina Zentiva

GNH USA supplies Levofloxacina Zentiva (Levofloxacin), a fluoroquinolone antibiotic for urinary, respiratory and skin infections. Request a quote for supply.

Levofloxacin Hemihydrate

Request sourcing

1
Pack/s

What is Levofloxacin Hemihydrate?

Levofloxacin, the active ingredient in Levofloxacina Zentiva, is a fluoroquinolone antibiotic presented as an oral tablet for oral use. Manufactured under EU quality standards, it treats a range of bacterial infections—including uncomplicated and complicated urinary tract infections, community‑acquired respiratory infections, skin and soft‑tissue infections, and prostatitis—in adult patients.

GNH USA supplies Levofloxacina Zentiva as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies, and clinics worldwide, providing reliable sourcing, regulatory documentation, and logistics support for global healthcare providers, and ensuring compliance with local import requirements.

What is Levofloxacin Hemihydrate used for?

Levofloxacina Zentiva, a fluoroquinolone antibacterial, is indicated for several bacterial infection categories.

- Urinary tract infections: effective against susceptible strains causing uncomplicated and complicated UTIs. - Respiratory tract infections: treats community‑acquired pneumonia and acute exacerbations of chronic bronchitis. - Skin and soft tissue infections: resolves infections of the skin, subcutaneous tissue, and wounds. - Prostatitis: eradicates bacterial pathogens responsible for chronic bacterial prostatitis.

What are the side effects of Levofloxacin Hemihydrate?

Levofloxacina Zentiva may cause adverse reactions ranging from mild to severe.

Common Side Effects: - Nausea - Diarrhea - Headache - Dizziness - Photosensitivity - Abdominal pain

Serious or Rare Side Effects: - Tendon rupture or tendinitis - QT interval prolongation - Severe allergic reactions (anaphylaxis, Stevens‑Johnson syndrome) - Clostridioides difficile‑associated diarrhea - Peripheral neuropathy - Hepatotoxicity

What precautions apply to Levofloxacin Hemihydrate?

Before prescribing Levofloxacina Zentiva, clinicians should consider several safety precautions.

- Renal function: adjust dose in patients with impaired renal function. - QT interval: avoid in patients with known QT prolongation or receiving other QT‑prolonging drugs. - Tendon disorders: avoid in patients with a history of tendon disease or recent corticosteroid therapy. - Pregnancy and lactation: use only if benefits outweigh potential risks. - Drug interactions: review concomitant medications for potential interactions. - Store at below 25°C: keep in original packaging, protect from moisture.

What does Levofloxacin Hemihydrate interact with?

Levofloxacina Zentiva interacts with several medicines; some combinations should be avoided while others require monitoring.

Major Interactions (Avoid): - Antacids containing aluminum or magnesium: reduce levofloxacin absorption. - Warfarin: may increase anticoagulant effect and bleeding risk.

Moderate Interactions (Monitor Closely): - Theophylline: increased plasma concentrations leading to toxicity. - Cyclosporine: elevated cyclosporine levels. - NSAIDs (e.g., ibuprofen): may increase risk of CNS stimulation and seizures.

Frequently asked questions

What is Levofloxacina Zentiva used for?+
Levofloxacina Zentiva contains levofloxacin, a fluoroquinolone antibiotic indicated for the treatment of bacterial infections such as urinary tract infections, community‑acquired respiratory infections, skin and soft‑tissue infections, and prostatitis in adult patients.
How does levofloxacin work?+
Levofloxacin blocks bacterial DNA gyrase and topoisomerase IV, enzymes required for DNA replication and transcription. This inhibition prevents the resealing of DNA strands, leading to bacterial cell death and a bactericidal effect against a wide range of pathogens.
What is the usual dose of Levofloxacina Zentiva?+
The prescribed dose of Levofloxacina Zentiva is determined by the treating physician based on the type and severity of infection, patient weight, renal function, and local guidelines. Typical adult regimens range from 250 mg to 750 mg once daily, but the exact schedule must be individualized.
Is Levofloxacina Zentiva safe during pregnancy or breastfeeding?+
Safety data for levofloxacin in pregnancy and lactation are limited. The drug should be used only when the potential benefit justifies any possible risk to the fetus or infant. Healthcare providers should discuss individual circumstances with the patient before prescribing.
How do I order Levofloxacina Zentiva from GNH USA?+
To place an order, submit an enquiry on the product page at gnh-usa.com, specifying the required quantity. GNH USA works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.
How does Levofloxacina Zentiva compare with other fluoroquinolones?+
Levofloxacina Zentiva offers a broad spectrum of activity similar to other fluoroquinolones but provides once‑daily dosing and higher potency against many Gram‑negative organisms compared with ciprofloxacin. Its safety profile is comparable, though all fluoroquinolones share risks such as tendon injury and QT prolongation.
What are the storage and handling requirements for Levofloxacina Zentiva?+
Store Levofloxacina Zentiva at temperatures below 25 °C in its original packaging, protecting it from moisture and direct sunlight. Do not expose the tablets to excessive heat or humidity, and keep them out of reach of children.
How is Levofloxacina Zentiva administered?+
Levofloxacina Zentiva is taken orally as a tablet with a full glass of water. It may be taken with or without food, but patients should swallow the tablet whole and avoid crushing or chewing to maintain proper absorption.
What are the most serious risks associated with Levofloxacina Zentiva?+
Serious adverse events include tendon rupture or tendinitis, QT interval prolongation leading to arrhythmias, severe allergic reactions such as anaphylaxis or Stevens‑Johnson syndrome, Clostridioides difficile‑associated colitis, peripheral neuropathy, and hepatic injury. Patients should seek immediate medical attention if any of these occur.
Who should not use Levofloxacina Zentiva?+
Levofloxacina Zentiva is contraindicated in individuals with known hypersensitivity to levofloxacin or other fluoroquinolones, those with a history of tendon disorders related to quinolone use, patients with prolonged QT interval, and individuals receiving concomitant medications that significantly increase the risk of QT prolongation. Caution is also advised for pregnant or breastfeeding women.
Information provided on this page is for educational use by procurement and clinical professionals. Always consult a licensed healthcare provider for medical advice and prescribing decisions. GNH USA supplies this product subject to applicable regulatory and licensing requirements.

Product details

Drug
Levofloxacin Hemihydrate
Route
Oral Use
Manufacturer
Zentiva Italia S.R.L.
Origin
EU

Related products