GNH USA

Europe — EMA

Levofloxacina Pharmazone

GNH USA supplies Levofloxacina Pharmazone (Levofloxacin), a fluoroquinolone antibiotic for urinary, respiratory, skin infections and prostatitis.

Levofloxacin Hemihydrate

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What is Levofloxacin Hemihydrate?

Levofloxacin, the active ingredient in Levofloxacina Pharmazone, is a fluoroquinolone antibiotic presented as an oral tablet for systemic use. It treats susceptible bacterial infections in adults and children when prescribed by a qualified health professional.

GNH USA supplies Levofloxacina Pharmazone as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

What is Levofloxacin Hemihydrate used for?

Levofloxacina Pharmazone is a fluoroquinolone antibiotic used to treat infections caused by susceptible bacteria.

- Urinary tract infection: eradicates the causative organisms and alleviates dysuria and frequency. - Respiratory tract infection: clears bacterial pathogens in conditions such as acute sinusitis and bronchitis. - Skin and soft‑tissue infection: resolves cellulitis, abscesses and wound infections. - Prostatitis: eliminates bacterial involvement in chronic bacterial prostatitis.

What are the side effects of Levofloxacin Hemihydrate?

Levofloxacina Pharmazone may cause a range of adverse reactions, most of which are mild and reversible.

Common Side Effects: - Nausea: mild stomach upset that often resolves without intervention. - Diarrhea: loose stools that may be self‑limiting. - Headache: transient cranial discomfort. - Dizziness: sensation of light‑headedness, especially on standing. - Insomnia: difficulty falling or staying asleep. - Rash: mild skin erythema or pruritus.

Serious or Rare Side Effects: - Tendon rupture: sudden tendon pain or loss of function, particularly in the Achilles. - QT interval prolongation: risk of cardiac arrhythmias, especially in patients with cardiac disease. - Severe allergic reaction: anaphylaxis with breathing difficulty, swelling, or hives. - Clostridioides difficile infection: severe colitis presenting with watery diarrhea. - Peripheral neuropathy: numbness or tingling in extremities. - Hepatic dysfunction: elevated liver enzymes or jaundice.

What precautions apply to Levofloxacin Hemihydrate?

Before prescribing Levofloxacina Pharmazone, clinicians should consider several safety aspects.

- Assess renal function: dose adjustment may be required in impaired clearance. - Avoid in patients with known tendon disorders: risk of tendon rupture is increased. - Monitor cardiac status: patients with QT prolongation risk should have ECG monitoring. - Use cautiously in the elderly: higher incidence of adverse events. - Avoid concomitant use with systemic glucocorticoids: may potentiate tendon toxicity. - Store at below 25°C: keep in the original pack, protect from moisture and direct sunlight.

What does Levofloxacin Hemihydrate interact with?

Levofloxacina Pharmazone can interact with several medicines, altering efficacy or safety.

Major Interactions (Avoid): - Antacids containing aluminum or magnesium: reduce levofloxacin absorption. - Ciprofloxacin: additive QT‑prolongation risk. - Warfarin: may increase INR and bleeding risk. - Theophylline: levofloxacin can raise serum theophylline levels. - Systemic glucocorticoids: increase risk of tendon rupture.

Moderate Interactions (Monitor Closely): - NSAIDs: combined gastrointestinal irritation. - Diabetes medications: possible alteration of glucose control. - Cyclosporine: may increase cyclosporine concentrations.

Frequently asked questions

What infections is Levofloxacina Pharmazone used to treat?+
Levofloxacina Pharmazone is prescribed for bacterial infections that are susceptible to levofloxacin, including urinary tract infections, respiratory tract infections such as sinusitis and bronchitis, skin and soft‑tissue infections, and chronic bacterial prostatitis. The drug targets the causative organisms to eradicate the infection.
How does levofloxacin work against bacteria?+
Levofloxacin blocks bacterial DNA gyrase and topoisomerase IV, enzymes required for DNA replication and transcription. By inhibiting these enzymes, the drug prevents bacterial DNA from unwinding and resealing, leading to bacterial cell death. This mechanism provides a broad‑spectrum bactericidal effect.
What is the usual dose of Levofloxacina Pharmazone?+
The dosage of Levofloxacina Pharmazone is determined by the prescribing clinician based on the type and severity of the infection, patient age, renal function, and other clinical factors. Patients should follow the exact dosing instructions provided by their healthcare professional.
Is Levofloxacina Pharmazone safe during pregnancy or breastfeeding?+
The safety of levofloxacin in pregnancy and lactation has not been definitively established. It is generally classified as contraindicated or used only when the potential benefit justifies the potential risk to the fetus. Breastfeeding mothers should consult their physician before use.
How do I order Levofloxacina Pharmazone from GNH USA?+
To place an order, submit an enquiry on the product page at gnh-usa.com, specifying the required quantity. GNH USA works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details, and any necessary import documentation.
How does Levofloxacina Pharmazone compare with other fluoroquinolones?+
Levofloxacina Pharmazone contains levofloxacin, the L‑isomer of ofloxacin, offering a higher potency and broader spectrum against Gram‑negative organisms compared with older fluoroquinolones. It also has a more favorable dosing schedule, often once daily, but shares class‑related safety considerations such as tendon and QT‑prolongation risks.
What are the recommended storage conditions for Levofloxacina Pharmazone?+
Levofloxacina Pharmazone tablets should be stored at temperatures below 25 °C, in a dry place, protected from moisture and direct sunlight. Keep the product in its original packaging until use to maintain stability.
How is Levofloxacina Pharmazone administered?+
Levofloxacina Pharmazone is taken orally, usually with a full glass of water. It can be taken with or without food, but patients should avoid concomitant intake of antacids or supplements containing calcium, magnesium, aluminum, or iron, as these may reduce absorption.
What are the most serious risks associated with Levofloxacina Pharmazone?+
Serious risks include tendon rupture (especially Achilles), QT interval prolongation leading to arrhythmias, severe allergic reactions such as anaphylaxis, Clostridioides difficile‑associated colitis, peripheral neuropathy, and hepatic injury. Patients should be educated to report any sudden joint pain, palpitations, or severe skin reactions promptly.
Who should not use Levofloxacina Pharmazone?+
Levofloxacina Pharmazone is contraindicated in patients with a known hypersensitivity to levofloxacin or other fluoroquinolones, those with a history of tendon disorders related to fluoroquinolone use, and individuals with certain cardiac conditions predisposing them to QT prolongation. Caution is also advised for patients with severe renal impairment.
Information provided on this page is for educational use by procurement and clinical professionals. Always consult a licensed healthcare provider for medical advice and prescribing decisions. GNH USA supplies this product subject to applicable regulatory and licensing requirements.

Product details

Drug
Levofloxacin Hemihydrate
Route
Oral Use
Manufacturer
Pharmazone Portugal Unipessoal Lda.
Origin
EU

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