Europe — EMA
Levofloxacina Accord
GNH USA supplies Levofloxacina Accord (Levofloxacin), a fluoroquinolone for pneumonia, bacterial sinusitis and urinary tract infections. Request a quote.
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What is Levofloxacin Hemihydrate?
Levofloxacin, the active ingredient in Levofloxacina Accord, is a fluoroquinolone presented as an oral dosage form for oral use. It treats bacterial infections such as community‑acquired pneumonia, acute bacterial sinusitis, urinary tract infections and skin and soft tissue infections in adult patients.
GNH USA supplies Levofloxacina Accord as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide. The company adheres to stringent quality standards and provides reliable sourcing for regulated markets. Its global distribution network ensures timely delivery and compliance with local regulatory requirements.
What is Levofloxacin Hemihydrate used for?
Levofloxacina Accord (levofloxacin) is used to treat bacterial infections in several organ systems. - Community‑acquired pneumonia: eradicates the causative bacteria, leading to clinical improvement and resolution of pulmonary infiltrates. - Acute bacterial sinusitis: reduces sinus inflammation by eliminating the infecting organisms, relieving congestion and facial pain. - Urinary tract infections: clears the urinary tract of susceptible pathogens, alleviating dysuria, frequency and systemic symptoms. - Skin and soft tissue infections: combats Gram‑negative and Gram‑positive bacteria, promoting healing of cellulitis, abscesses and wound infections.
What are the side effects of Levofloxacin Hemihydrate?
Levofloxacina Accord may cause a range of adverse reactions, which are classified by frequency and severity.
Common Side Effects: - Nausea: mild to moderate stomach upset. - Diarrhea: loose, sometimes watery stools. - Headache: transient cranial discomfort. - Dizziness: sensation of light‑headedness or imbalance.
Serious or Rare Side Effects: - Tendon rupture or tendinitis: especially Achilles, may occur during or after therapy. - QT interval prolongation: can lead to cardiac arrhythmias. - Severe hypersensitivity reactions: including Stevens‑Johnson syndrome, toxic epidermal necrolysis, or anaphylaxis.
What precautions apply to Levofloxacin Hemihydrate?
Levofloxacina Accord requires careful use in specific patient groups and conditions. - Renal function: adjust use in patients with impaired kidney function and monitor serum creatinine. - Age considerations: use cautiously in elderly patients due to increased risk of tendon injury. - Phototoxicity: advise patients to avoid excessive sunlight or UV exposure during treatment. - Drug resistance: limit use to confirmed bacterial infections to reduce development of resistance. - Pregnancy and lactation: avoid unless clearly needed; safety data are limited. - Store at below 25°C: keep in the original container, protect from moisture and heat.
What does Levofloxacin Hemihydrate interact with?
Levofloxacina Accord can interact with several medicines, requiring avoidance or close monitoring.
Major Interactions (Avoid): - Antacids containing aluminum or magnesium: reduce levofloxacin absorption; separate dosing by at least 2 hours. - Non‑steroidal anti‑inflammatory drugs (NSAIDs): increase risk of central nervous system stimulation and seizures. - Warfarin: may enhance anticoagulant effect, requiring close INR monitoring. - Theophylline: levofloxacin can increase serum theophylline levels, risking toxicity.
Moderate Interactions (Monitor Closely): - Corticosteroids: combined use may raise risk of tendon rupture. - Diabetic agents (e.g., insulin, sulfonylureas): levofloxacin may cause dysglycemia; monitor blood glucose. - Cyclosporine: may increase cyclosporine concentrations; monitor levels.
Frequently asked questions
What is Levofloxacina Accord used for?+
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