Levofloxacin/Rafarm [pf]

Levofloxacin, the active ingredient in Levofloxacin/Rafarm [pf], is a fluoroquinolone presented as an ophthalmic preparation for ocular use. It treats bacterial eye infections such as conjunctivitis and keratitis in both adult and pediatric patients.

GNH USA supplies Levofloxacin/Rafarm [pf] as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide, providing quality‑assured products that meet EU regulatory standards.

Levofloxacin is a fluoroquinolone antibiotic indicated for bacterial infections of the eye.

- Bacterial conjunctivitis: reduces bacterial load and alleviates symptoms such as redness, discharge and irritation. - Bacterial keratitis: eradicates causative organisms and supports corneal healing, helping to preserve visual acuity.

Levofloxacin ophthalmic solution may cause local and systemic adverse reactions.

Common Side Effects: - Eye irritation or burning sensation. - Redness of the conjunctiva. - Tearing or increased lacrimation. - Transient blurred vision. - Foreign‑body sensation. - Mild itching.

Serious or Rare Side Effects: - Allergic reactions such as eyelid edema, rash or urticaria. - Corneal ulceration or severe keratitis. - Vision loss or sudden decrease in visual acuity. - Stevens‑Johnson syndrome or toxic epidermal necrolysis involving the ocular surface. - Persistent severe eye pain.

Levofloxacin ophthalmic solution should be used with caution and under professional supervision.

- Hypersensitivity: discontinue if any signs of allergic reaction appear. - Corneal disease: avoid in patients with active corneal ulcer unless specifically indicated. - Contact lenses: remove lenses during treatment and re‑insert only after therapy completion. - Concomitant steroids: monitor closely as combined use may increase risk of infection. - Pediatric use: follow ophthalmologist guidance for dosing and duration. - Store at room temperature: keep in original container, protect from light and moisture.

Levofloxacin ophthalmic solution can interact with other ocular or systemic agents.

Major Interactions (Avoid): - Co‑administration with other fluoroquinolone eye drops may increase local toxicity. - Systemic fluoroquinolones combined with corticosteroids can raise the risk of tendon rupture.

Moderate Interactions (Monitor Closely): - Use with anticholinergic eye drops may reduce drug penetration. - Concurrent use of non‑steroidal anti‑inflammatory eye drops may heighten irritation. - Systemic cation‑containing supplements (e.g., calcium, iron) can reduce overall fluoroquinolone exposure if systemic absorption occurs.