Levofloxacin/Rafarm (Pf)

Levofloxacin, the active ingredient in Levofloxacin/Rafarm, is a fluoroquinolone antibiotic presented as a sterile ophthalmic solution for ocular use. It treats bacterial conjunctivitis, keratitis and other ocular bacterial infections in patients requiring topical therapy.

GNH USA supplies Levofloxacin/Rafarm as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide. The company adheres to stringent quality standards and provides regulatory‑approved batches to meet global demand. Customers benefit from reliable logistics, comprehensive documentation and responsive technical support throughout the procurement process.

Levofloxacin ophthalmic solution is indicated for bacterial infections of the eye and related structures.

- Bacterial conjunctivitis: reduces bacterial load and accelerates resolution of redness, discharge and irritation. - Keratitis: eradicates causative bacteria, promoting corneal healing and visual recovery. - Other ocular bacterial infections: treats blepharitis, corneal ulceration and postoperative infections by targeting susceptible organisms.

Topical levofloxacin may cause local and systemic adverse reactions, most of which are mild and reversible.

Common Side Effects: - Eye irritation: transient burning or stinging upon instillation. - Redness: mild conjunctival hyperemia. - Tearing: increased lacrimation. - Foreign body sensation: feeling of grit in the eye. - Blurred vision: temporary visual disturbance.

Serious or Rare Side Effects: - Corneal ulceration: worsening of corneal lesions. - Allergic keratitis: immune‑mediated inflammation. - Stevens‑Johnson syndrome: severe mucocutaneous reaction. - Anaphylaxis: systemic hypersensitivity with respiratory compromise.

Before using Levofloxacin ophthalmic solution, consider the following precautions.

- Assess infection: confirm bacterial etiology before initiating therapy. - Monitor response: re‑evaluate after 48‑72 hours and discontinue if no improvement. - Avoid in hypersensitivity: do not use in patients with known levofloxacin or fluoroquinolone allergy. - Caution in corneal disease: use with care in patients with epithelial defects or severe keratitis. - Pregnancy and lactation: safety not established; prescribe only if benefit outweighs risk. - Store at room temperature: keep below 25 °C, protect from light and moisture in original container.

Levofloxacin ophthalmic solution can interact with other ocular or systemic agents.

Major Interactions (Avoid): - Systemic fluoroquinolones: concurrent use may increase risk of tendon rupture. - Anticholinergic eye drops: may reduce pupil dilation effect. - Corticosteroid eye preparations: may mask infection signs and delay healing.

Moderate Interactions (Monitor Closely): - NSAID eye drops: potential additive ocular irritation. - Herbal supplements containing quinine: may potentiate QT prolongation. - Diabetes medications: monitor blood glucose as ocular inflammation can affect control.