GNH USA

Europe — EMA

Levofloxacin Orion

GNH USA supplies Levofloxacin Orion (Levofloxacin), a fluoroquinolone antibiotic for respiratory, urinary and skin infections. Request a quote for supply.

Levofloxacin

Request sourcing

1
Pack/s

What is Levofloxacin?

Levofloxacin, the active ingredient in Levofloxacin Orion, is a fluoroquinolone antibiotic presented as an oral tablet for oral use. It treats a range of bacterial infections in adults and adolescents, including respiratory, urinary and skin infections. It is indicated for community‑acquired respiratory tract infections, acute bacterial sinusitis, chronic bronchitis exacerbations, uncomplicated and complicated urinary tract infections, as well as skin and soft‑tissue infections.

GNH USA supplies Levofloxacin Orion as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide. The company adheres to stringent quality standards and provides regulatory documentation for importers.

What is Levofloxacin used for?

Levofloxacin is a fluoroquinolone antibiotic that interferes with bacterial DNA processes across several infection categories. - Community‑acquired respiratory tract infections: eradicates the causative bacteria and resolves symptoms. - Acute bacterial sinusitis: clears sinus pathogens and improves nasal drainage. - Acute exacerbations of chronic bronchitis: reduces bacterial load and alleviates cough. - Uncomplicated urinary tract infections: eliminates uropathogens and restores urinary health. - Skin and soft‑tissue infections: treats bacterial cellulitis and related dermal conditions.

What are the side effects of Levofloxacin?

Levofloxacin may cause a range of adverse reactions, from mild to severe.

Common Side Effects: - Nausea: mild gastrointestinal upset. - Diarrhea: loose stools, often self‑limiting. - Headache: transient cranial discomfort. - Dizziness: occasional vertigo or light‑headedness.

Serious or Rare Side Effects: - Tendon rupture: risk of Achilles or other tendon tears. - QT interval prolongation: potential cardiac arrhythmias. - Severe allergic reactions: anaphylaxis, Stevens‑Johnson syndrome.

What precautions apply to Levofloxacin?

Levofloxacin requires careful use in specific patient groups. - Renal function: adjust dosing in severe impairment. - History of tendon disorders: avoid use due to rupture risk. - Concomitant QT‑prolonging drugs: monitor ECG for arrhythmias. - Pregnancy and lactation: use only if benefits outweigh potential risks. - Age: exercise caution in elderly patients because of increased adverse event susceptibility. - Store at ambient temperature: keep in the original container, protect from moisture and light.

What does Levofloxacin interact with?

Levofloxacin can interact with other medicines, altering efficacy or safety.

Major Interactions (Avoid): - Antacids containing aluminum or magnesium: markedly reduce levofloxacin absorption. - Warfarin: may potentiate anticoagulant effect and increase bleeding risk.

Moderate Interactions (Monitor Closely): - Corticosteroids: heightened risk of tendon rupture. - Theophylline: levofloxacin may increase plasma theophylline concentrations. - NSAIDs: potential for increased central nervous system stimulation.

Frequently asked questions

What infections is Levofloxacin Orion used to treat?+
Levofloxacin Orion is prescribed for a variety of bacterial infections, including community‑acquired respiratory tract infections, acute bacterial sinusitis, exacerbations of chronic bronchitis, uncomplicated and complicated urinary tract infections, as well as skin and soft‑tissue infections. The specific indication depends on the clinician’s assessment of the infection type and severity.
How does levofloxacin work against bacteria?+
Levofloxacin blocks bacterial DNA gyrase and topoisomerase IV, enzymes that control DNA supercoiling and replication. By inhibiting these targets, the drug prevents bacterial DNA synthesis and transcription, leading to bacterial cell death. This mechanism gives levofloxacin a broad spectrum of activity against many Gram‑negative and Gram‑positive organisms.
What is the usual dose of Levofloxacin Orion?+
The dosage of Levofloxacin Orion is determined by the prescribing healthcare professional based on the infection being treated, patient age, renal function, and other clinical factors. Patients should follow the prescriber’s instructions and not alter the dose without medical advice.
Is Levofloxacin Orion safe during pregnancy or breastfeeding?+
Safety data for levofloxacin in pregnancy and lactation are limited. It should only be used when the potential benefit to the mother outweighs any possible risk to the fetus or infant. Healthcare providers will evaluate the risk‑benefit profile before prescribing to pregnant or nursing individuals.
How do I order Levofloxacin Orion from GNH USA?+
To request Levofloxacin Orion, submit an enquiry on the product page at gnh-usa.com, specifying the required quantity. GNH USA works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including any cold‑chain requirements), and necessary import documentation.
How does Levofloxacin compare with other fluoroquinolones?+
Levofloxacin is the L‑isomer of ofloxacin and generally offers higher potency, better tissue penetration, and a more convenient once‑daily dosing schedule compared with many older fluoroquinolones. Its spectrum covers many respiratory, urinary, and skin pathogens, making it a preferred option when a broad‑spectrum oral agent is needed.
What are the storage requirements for Levofloxacin Orion?+
Levofloxacin Orion should be stored at ambient temperature, below 25 °C. Keep the tablets in the original packaging, protect them from moisture, excessive heat, and direct sunlight to maintain potency throughout the shelf life.
How is Levofloxacin Orion administered?+
Levofloxacin Orion is taken orally, usually with a full glass of water. It can be taken with or without food, but patients should avoid concurrent intake of antacids containing aluminum or magnesium, as these can reduce drug absorption. Swallow the tablet whole; do not crush or chew.
What are the most serious risks associated with Levofloxacin Orion?+
Serious adverse events include tendon rupture (especially in the Achilles tendon), QT‑interval prolongation leading to cardiac arrhythmias, severe allergic reactions such as anaphylaxis or Stevens‑Johnson syndrome, and Clostridioides difficile‑associated diarrhea. Patients should seek immediate medical attention if they experience sudden tendon pain, palpitations, or severe skin reactions.
Who should not use Levofloxacin Orion?+
Levofloxacin Orion is contraindicated in individuals with a known hypersensitivity to levofloxacin, other fluoroquinolones, or any of the tablet’s excipients. It should also be avoided in patients with a history of tendon disorders related to fluoroquinolone use, those taking concurrent QT‑prolonging drugs without monitoring, and in certain pregnancy or lactation scenarios where risks outweigh benefits.
Information provided on this page is for educational use by procurement and clinical professionals. Always consult a licensed healthcare provider for medical advice and prescribing decisions. GNH USA supplies this product subject to applicable regulatory and licensing requirements.

Product details

Drug
Levofloxacin
Route
Oral Use
Manufacturer
Orion Corporation
Origin
EU

Related products