Levofloxacin Krka

Levofloxacin, the active ingredient in Levofloxacin Krka, is a fluoroquinolone presented as an oral tablet for oral use. It treats a range of bacterial infections in adults and children as prescribed.

GNH USA supplies Levofloxacin Krka as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Levofloxacin is a broad‑spectrum antibacterial indicated for several common bacterial infections. - Community‑acquired pneumonia: eradicates the causative pathogens and improves respiratory function. - Acute bacterial sinusitis: reduces sinus inflammation and clears infection. - Acute bacterial exacerbation of chronic bronchitis: shortens symptom duration and prevents complications. - Urinary tract infections: eliminates uropathogens and resolves urinary symptoms. - Skin and soft‑tissue infections: treats cellulitis and related bacterial skin conditions.

Levofloxacin may cause a range of adverse reactions, from mild to severe.

Common Side Effects: - Nausea: mild gastrointestinal upset. - Diarrhea: loose stools, often self‑limited. - Headache: transient cranial discomfort. - Dizziness: occasional vertigo or light‑headedness. - Rash: mild skin erythema. - Photosensitivity: increased sensitivity to sunlight.

Serious or Rare Side Effects: - Tendon rupture: especially Achilles tendon, may occur without warning. - QT prolongation: cardiac rhythm disturbance requiring monitoring. - Severe hypersensitivity: anaphylaxis or Stevens‑Johnson syndrome. - Central nervous system effects: seizures or psychosis in susceptible individuals.

Levofloxacin should be used with caution and under professional supervision. - Renal impairment: dose adjustment may be required. - History of tendon disorders: avoid use if prior tendon injury. - Cardiac arrhythmias: monitor QT interval in patients with known prolongation. - Pregnancy and lactation: safety not established; weigh risks and benefits. - Concomitant medications: review for potential interactions before prescribing. - Store at ambient temperature: keep below 25 °C, retain in original packaging, protect from moisture and direct sunlight.

Levofloxacin can interact with several drug classes, affecting efficacy or safety.

Major Interactions (Avoid): - Antacids containing aluminum or magnesium: reduce levofloxacin absorption. - Warfarin: may increase anticoagulant effect and bleeding risk. - NSAIDs (e.g., ibuprofen): heightened risk of central nervous system stimulation.

Moderate Interactions (Monitor Closely): - Theophylline: may increase serum theophylline levels. - Cyclosporine: potential for increased nephrotoxicity. - Corticosteroids: combined use may raise tendon‑rupture risk.