Levofloxacin Krka

Levofloxacin, the active ingredient in Levofloxacin Krka, is a fluoroquinolone presented as a tablet for oral use. It treats bacterial infections of the respiratory, urinary and skin systems in adult patients. GNH USA supplies Levofloxacin Krka as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Levofloxacin is an antibacterial agent used to treat infections caused by susceptible bacteria in several organ systems. - Respiratory tract infections: eradicates pathogens responsible for community‑acquired pneumonia and acute bronchitis. - Urinary tract infections: eliminates common uropathogens causing cystitis and pyelonephritis. - Skin and soft tissue infections: resolves bacterial cellulitis, wound infections and abscesses. - Sinusitis: clears infection of the paranasal sinuses. - Prostatitis: treats chronic bacterial prostatitis. - Community‑acquired pneumonia: provides coverage for typical and atypical organisms.

Levofloxacin may cause a range of adverse reactions, from mild to severe.

Common Side Effects: - Nausea - Diarrhea - Headache - Dizziness - Abdominal pain - Insomnia

Serious or Rare Side Effects: - Tendon rupture or tendinitis - QT interval prolongation - Severe allergic reactions (anaphylaxis) - Clostridioides difficile‑associated colitis - Peripheral neuropathy - Hepatic dysfunction

Levofloxacin should be used with caution in specific clinical situations. - Assess renal function: adjust dose in patients with impaired clearance. - Review history of tendon disorders: avoid in individuals with recent tendon injury or surgery. - Monitor QT interval: use cautiously with other QT‑prolonging agents. - Evaluate for hypersensitivity: discontinue if rash, angioedema or anaphylaxis occurs. - Avoid use in pregnancy unless essential: limited safety data are available. - Store at room temperature: keep in the original container, protect from moisture and light.

Levofloxacin can interact with several medicines, requiring attention to avoid adverse outcomes.

Major Interactions (Avoid): - Antacids containing aluminum or magnesium: reduce levofloxacin absorption. - Warfarin: potentiates anticoagulant effect, increasing bleeding risk. - Theophylline: may raise theophylline plasma levels, risking toxicity.

Moderate Interactions (Monitor Closely): - NSAIDs: combined use may increase risk of tendon disorders. - Corticosteroids: additive risk of tendon rupture. - Diabetic agents (insulin, sulfonylureas): levofloxacin can enhance hypoglycaemic effect.