GNH USA

Europe — EMA

Levofloxacin Hikma

GNH USA supplies Levofloxacin Hikma (Levofloxacin), a fluoroquinolone antibiotic for treatment of susceptible bacterial infections.

Levofloxacin

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What is Levofloxacin?

Levofloxacin, the active ingredient in Levofloxacin Hikma, is a fluoroquinolone antibiotic presented as an intravenous formulation for intravenous use. It treats susceptible bacterial infections in adult patients when prescribed by a qualified health professional.

GNH USA supplies Levofloxacin Hikma as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals worldwide.

What is Levofloxacin used for?

Levofloxacin is a broad‑spectrum fluoroquinolone used to treat infections caused by susceptible bacteria.

- Community‑acquired pneumonia: eradicates the typical and atypical pathogens responsible for the infection. - Urinary tract infection: eliminates causative Gram‑negative and some Gram‑positive organisms. - Skin and soft‑tissue infection: resolves infections caused by susceptible Staphylococcus and Streptococcus species.

What are the side effects of Levofloxacin?

Levofloxacin may cause a variety of adverse reactions, ranging from mild to severe.

Common Side Effects: - Nausea: mild to moderate upset stomach. - Diarrhea: loose stools, sometimes watery. - Headache: transient cranial discomfort. - Dizziness: sensation of light‑headedness. - Insomnia: difficulty falling or staying asleep. - Rash: mild skin erythema.

Serious or Rare Side Effects: - Tendon rupture: sudden tendon pain or loss of function. - QT interval prolongation: risk of cardiac arrhythmias. - Clostridioides difficile infection: severe colitis. - Anaphylaxis: life‑threatening allergic reaction. - Stevens‑Johnson syndrome: severe skin and mucous membrane disorder. - Peripheral neuropathy: numbness or tingling in extremities.

What precautions apply to Levofloxacin?

Levofloxacin should be used with caution in specific clinical situations.

- Renal impairment: dose adjustment may be required. - History of tendon disorders: avoid use due to rupture risk. - QT prolongation risk: monitor cardiac rhythm in susceptible patients. - Pregnancy and lactation: prescribe only when benefits outweigh potential risks. - Concurrent antacids or supplements: separate administration to prevent reduced absorption. - Store at 2-8°C: keep refrigerated, protect from light, do not freeze.

What does Levofloxacin interact with?

Levofloxacin can interact with several medicines, influencing safety or efficacy.

Major Interactions (Avoid): - Ciprofloxacin: additive QT‑prolongation effect. - Warfarin: increased anticoagulant effect, monitor INR closely. - Theophylline: elevated serum theophylline levels, risk of toxicity.

Moderate Interactions (Monitor Closely): - NSAIDs: heightened risk of renal impairment. - Corticosteroids: increased chance of tendon rupture. - Antacids containing aluminum or magnesium: may decrease levofloxacin absorption.

Frequently asked questions

What infections is Levofloxacin Hikma used to treat?+
Levofloxacin Hikma is indicated for the treatment of susceptible bacterial infections such as community‑acquired pneumonia, urinary tract infections, and skin and soft‑tissue infections. It is prescribed by a qualified clinician based on culture results and clinical judgment.
How does levofloxacin work against bacteria?+
Levofloxacin blocks bacterial DNA gyrase and topoisomerase IV, enzymes required for DNA replication and transcription. This inhibition prevents bacterial cells from dividing, leading to rapid bactericidal activity against a broad range of Gram‑negative and Gram‑positive organisms.
What is the usual dose of Levofloxacin Hikma?+
The dosage of Levofloxacin Hikma is determined by the prescribing physician according to the type and severity of infection, patient weight, renal function, and other clinical factors. The prescriber sets the exact dose and duration.
Is Levofloxacin safe to use during pregnancy or breastfeeding?+
Levofloxacin is classified as pregnancy category unknown. It should be used during pregnancy or lactation only when the potential benefit justifies the potential risk to the fetus or infant. The prescribing clinician must evaluate each case individually.
How do I order Levofloxacin Hikma from GNH USA?+
To place an order, submit an enquiry on the product page at gnh-usa.com, specifying the required quantity. GNH USA works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including any cold‑chain requirements), and necessary import documentation.
How does Levofloxacin compare with other fluoroquinolones?+
Levofloxacin is a third‑generation fluoroquinolone with enhanced activity against Gram‑positive organisms compared with older agents like ciprofloxacin. It offers once‑daily dosing for many infections and a favorable safety profile, though all fluoroquinolones share class‑related warnings such as tendon toxicity and QT prolongation.
What are the storage and handling requirements for Levofloxacin Hikma?+
Levofloxacin Hikma should be stored at 2‑8 °C, protected from light, and kept in its original packaging. Do not freeze the product, and avoid exposing it to excessive heat or moisture to maintain stability.
How is Levofloxacin Hikma administered?+
Levofloxacin Hikma is supplied as an intravenous solution and is administered by slow infusion into a vein under the supervision of a qualified health professional. The infusion rate and duration are set by the prescriber based on the clinical scenario.
What are the most serious risks associated with Levofloxacin Hikma?+
Serious risks include tendon rupture, especially in older adults or those on corticosteroids; QT interval prolongation leading to arrhythmias; severe allergic reactions such as anaphylaxis; and Clostridioides difficile‑associated colitis. Patients should be monitored closely for these events.
Who should not use Levofloxacin Hikma?+
Levofloxacin should be avoided in patients with a known hypersensitivity to fluoroquinolones, a history of tendon disorders related to quinolone use, or those with significant QT prolongation. Caution is also advised for patients with severe renal impairment unless dose adjustments are made.
Information provided on this page is for educational use by procurement and clinical professionals. Always consult a licensed healthcare provider for medical advice and prescribing decisions. GNH USA supplies this product subject to applicable regulatory and licensing requirements.

Product details

Drug
Levofloxacin
Route
Intravenous Use
Manufacturer
Hikma Farmacêutica (Portugal), S.A.
Origin
EU

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