Levofloxacin Hemihydrate Aurobindo

Levofloxacin, the active ingredient in Levofloxacin Hemihydrate Aurobindo, is a fluoroquinolone antibiotic presented as an oral tablet for oral use. It treats a range of bacterial infections in adults and children as prescribed.

GNH USA supplies Levofloxacin Hemihydrate Aurobindo as a licensed, GDP-compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Levofloxacin is a broad‑spectrum fluoroquinolone used to treat bacterial infections in several organ systems.

Community‑acquired respiratory tract infection: eradicates causative bacteria and improves respiratory symptoms. Urinary tract infection: eliminates uropathogens and resolves urinary symptoms. Skin and soft tissue infection: clears bacterial involvement and promotes wound healing. Acute bacterial sinusitis: reduces sinus inflammation by targeting the infecting organisms. Acute bacterial prostatitis: achieves bacterial eradication within the prostate gland.

Levofloxacin may cause a range of adverse reactions, from mild to severe.

Common Side Effects: - Nausea - Diarrhea - Headache - Dizziness

Serious or Rare Side Effects: - Tendon rupture or inflammation - QT‑interval prolongation and cardiac arrhythmia - Clostridioides difficile‑associated colitis - Severe allergic reactions such as Stevens‑Johnson syndrome

Levofloxacin requires careful consideration of patient‑specific factors and proper handling.

Assess renal function: adjust dosing in patients with impaired clearance. Monitor for tendon pain: discontinue therapy if tendonitis or rupture is suspected. Avoid in patients with known hypersensitivity to fluoroquinolones. Use with caution in pregnancy or breastfeeding: risk category is unknown. Store at room temperature: keep in the original container, protect from moisture and light.

Levofloxacin can interact with several medicines, necessitating monitoring or avoidance.

Major Interactions (Avoid): - Systemic corticosteroids: increased risk of tendon rupture. - Antacids containing aluminum or magnesium: markedly reduced levofloxacin absorption. - Warfarin: potential enhancement of anticoagulant effect. - Other QT‑prolonging drugs: heightened risk of cardiac arrhythmias.

Moderate Interactions (Monitor Closely): - NSAIDs: may increase central nervous system adverse effects. - Theophylline: levofloxacin can raise plasma theophylline concentrations. - CYP450 inducers (e.g., rifampin): may lower levofloxacin exposure and efficacy.