GNH USA

Europe — EMA

Levofloxacină Atb

GNH USA supplies Levofloxacină Atb (Levofloxacin), a fluoroquinolone antibiotic for respiratory, urinary and skin infections.

Levofloxacin Hemihydrate

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What is Levofloxacin Hemihydrate?

Levofloxacin, the active ingredient in Levofloxacină Atb, is a fluoroquinolone antibiotic presented as a tablet for oral use. It treats a range of bacterial infections in adults, including community‑acquired pneumonia, urinary tract infections, and skin infections. It is indicated for adult patients with acute bacterial sinusitis, chronic bronchitis exacerbations, and other serious infections where susceptible organisms are identified.

GNH USA supplies Levofloxacină Atb as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide, providing regulated channels that ensure product quality and compliance with EU standards.

What is Levofloxacin Hemihydrate used for?

Levofloxacin is a fluoroquinolone antibiotic used to treat bacterial infections of the respiratory, urinary, and skin systems.

- Community-acquired pneumonia: eliminates the typical bacterial pathogens, aiding recovery of lung function. - Acute bacterial sinusitis: reduces sinus inflammation by clearing the infecting organisms. - Acute exacerbations of chronic bronchitis: treats bacterial flare‑ups, helping restore airway patency. - Urinary tract infections: eradicates uropathogens, relieving dysuria and preventing complications. - Skin and soft tissue infections: combats susceptible bacteria, promoting wound healing.

What are the side effects of Levofloxacin Hemihydrate?

Levofloxacin may cause several adverse reactions, ranging from mild to potentially serious.

Common Side Effects: - Nausea: upset stomach often occurring shortly after dosing. - Diarrhea: loose stools that may be watery. - Headache: mild to moderate head pain. - Dizziness: sensation of lightheadedness or imbalance. - Insomnia: difficulty falling or staying asleep. - Abdominal pain: discomfort in the stomach area.

Serious or Rare Side Effects: - Tendon rupture: sudden tendon failure, especially in the Achilles. - QT interval prolongation: heart rhythm disturbance that can lead to arrhythmia. - Severe allergic reactions: rash, swelling, or anaphylaxis. - Clostridioides difficile infection: severe colitis following antibiotic use. - Peripheral neuropathy: nerve pain or weakness. - Stevens-Johnson syndrome: serious skin and mucous membrane reaction.

What precautions apply to Levofloxacin Hemihydrate?

Levofloxacin should be used with caution in specific patient groups and clinical situations.

- Assess renal function: adjust dose in impaired patients. - Avoid use in patients with known tendon disorders: risk of tendon rupture. - Monitor for QT prolongation: especially with concomitant QT‑prolonging drugs. - Consider pregnancy category B: weigh benefits versus potential risks. - Avoid in children unless no alternatives: fluoroquinolones are generally not first‑line in pediatrics. - Store at ambient temperature: keep in the original pack, protect from moisture and light.

What does Levofloxacin Hemihydrate interact with?

Levofloxacin can interact with other medicines, altering its effectiveness or safety profile.

Major Interactions (Avoid): - Antacids containing aluminum, magnesium, or calcium: reduce levofloxacin absorption. - Warfarin: may increase bleeding risk. - Other QT‑prolonging agents: heightened risk of cardiac arrhythmias.

Moderate Interactions (Monitor Closely): - Non‑steroidal anti‑inflammatory drugs (NSAIDs): may increase central nervous system effects. - Theophylline: levofloxacin can raise plasma theophylline levels. - Corticosteroids: combined use may increase tendon rupture risk.

Frequently asked questions

What is Levofloxacină Atb used for?+
Levofloxacină Atb contains levofloxacin, a fluoroquinolone antibiotic indicated for adult patients with community‑acquired pneumonia, acute bacterial sinusitis, exacerbations of chronic bronchitis, urinary tract infections, and skin or soft‑tissue infections caused by susceptible bacteria.
How does levofloxacin work?+
Levofloxacin acts by inhibiting bacterial DNA gyrase and topoisomerase IV, enzymes required for DNA supercoiling and replication. This blockade prevents bacterial cells from duplicating their genetic material, leading to bacterial death and resolution of the infection.
What is the usual dose of Levofloxacină Atb?+
The appropriate dose of Levofloxacină Atb is determined by the prescribing clinician based on the specific infection, patient characteristics, and local guidelines. Dosage may vary according to severity, renal function, and susceptibility patterns.
Is Levofloxacină Atb safe in pregnancy or breastfeeding?+
Levofloxacin is classified as pregnancy category B, indicating that animal studies have not shown risk but there are no well‑controlled studies in pregnant women. It should be used only if the potential benefit justifies any potential risk to the fetus. Breastfeeding mothers should consult their healthcare provider.
How do I order Levofloxacină Atb from GNH USA?+
To order, submit an enquiry on the product page at gnh-usa.com specifying the required quantity. GNH USA supplies hospitals, pharmacies and procurement teams worldwide, and will request trade or institutional credentials before providing pricing, availability, shipping details and import documentation.
How does levofloxacin compare with other fluoroquinolones?+
Levofloxacin offers a broad spectrum of activity similar to ciprofloxacin but with enhanced potency against Gram‑positive organisms and better lung penetration than many older fluoroquinolones. Compared with moxifloxacin, it has a slightly different safety profile, particularly regarding tendon‑related risks.
What are the storage and handling requirements for Levofloxacină Atb?+
Levofloxacină Atb tablets should be stored at ambient temperature, below 25 °C, in the original container to protect from moisture and light. Keep the product out of reach of children and avoid exposing it to excessive heat.
How is Levofloxacină Atb administered?+
The medication is taken orally as a tablet, swallowed whole with a full glass of water. It may be taken with or without food, but consistent administration with respect to meals helps maintain stable absorption.
What are the most serious risks associated with levofloxacin?+
Serious adverse events include tendon rupture, especially of the Achilles tendon, QT‑interval prolongation leading to cardiac arrhythmias, severe allergic reactions such as anaphylaxis, and Clostridioides difficile‑associated colitis. Prompt medical attention is required if any of these occur.
Who should not use Levofloxacină Atb?+
Levofloxacin should be avoided in individuals with a known hypersensitivity to levofloxacin or other fluoroquinolones, those with a history of tendon disorders related to fluoroquinolone use, and in children or adolescents unless no alternative therapy exists.
Information provided on this page is for educational use by procurement and clinical professionals. Always consult a licensed healthcare provider for medical advice and prescribing decisions. GNH USA supplies this product subject to applicable regulatory and licensing requirements.

Product details

Drug
Levofloxacin Hemihydrate
Route
Oral Use
Manufacturer
Antibiotice Sa
Origin
EU

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