Levofloxacin Eberth (Levofloxacin Hemihydrate)

Levofloxacin, the active ingredient in Levofloxacin Eberth, is a fluoroquinolone antibiotic presented as an intravenous solution for intravenous use. It treats susceptible bacterial infections in adult patients.

GNH USA supplies Levofloxacin Eberth as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Levofloxacin is a broad‑spectrum fluoroquinolone used to treat bacterial infections in various organ systems.

Community‑acquired pneumonia: eradicates causative bacteria and improves clinical outcomes. Hospital‑acquired pneumonia: effective against Gram‑negative pathogens, reducing infection severity. Complicated urinary tract infection: clears infection and helps prevent recurrence. Skin and soft‑tissue infection: treats bacterial skin infections and promotes healing.

Levofloxacin may cause a range of adverse reactions, from mild to severe.

Common Side Effects: - Nausea or vomiting - Diarrhea - Headache - Dizziness - Rash or mild skin irritation - Transient elevation of liver enzymes

Serious or Rare Side Effects: - Tendon rupture or tendinitis - QT interval prolongation and cardiac arrhythmias - Severe allergic reactions, including anaphylaxis - Clostridioides difficile‑associated colitis - Hepatic failure or severe liver injury - Central nervous system effects such as seizures or psychosis

Levofloxacin requires careful assessment of patient risk factors before use. - Renal impairment: adjust dosing and monitor renal function. - Hepatic impairment: monitor liver enzymes and consider dose modification. - Cardiac risk: avoid in patients with known QT prolongation or arrhythmias. - Tendon injury: advise patients to report tendon pain, especially in older adults. - Pregnancy and lactation: use only if clearly needed, as safety data are limited. - Store at room temperature: keep in original container, protect from light and moisture.

Levofloxacin can interact with several medicines, altering efficacy or safety.

Major Interactions (Avoid): - Antacids or supplements containing aluminum, magnesium, calcium, or iron: may reduce drug absorption. - Warfarin: increased anticoagulant effect, risk of bleeding. - Theophylline: elevated plasma levels, risk of toxicity. - Cyclosporine: higher levofloxacin concentrations, potential toxicity. - Other fluoroquinolones: additive risk of QT prolongation.

Moderate Interactions (Monitor Closely): - NSAIDs: enhanced central nervous system side effects. - Corticosteroids: increased risk of tendon rupture. - Oral contraceptives: possible reduction in contraceptive efficacy. - Diabetic agents: may affect glucose control. - Certain antivirals (e.g., zidovudine): potential for increased adverse effects.