Levofloxacin Al

Levofloxacin, the active ingredient in Levofloxacin Al, is a fluoroquinolone presented as an oral tablet for oral use. It treats a range of serious bacterial infections, including community‑acquired respiratory, urinary, skin and intra‑abdominal infections, in adult patients, and is often selected when alternative agents are unsuitable.

GNH USA supplies Levofloxacin Al as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide, with reliable quality assurance, on‑time delivery, adherence to stringent regulatory standards, and comprehensive technical support for global partners.

Levofloxacin is a fluoroquinolone antibiotic that targets bacterial DNA replication in various infection types.

- Community‑acquired pneumonia: eradicates the causative bacteria to improve respiratory function and reduce disease duration. - Acute exacerbation of chronic bronchitis: provides bacterial coverage to alleviate symptoms and prevent progression. - Uncomplicated urinary tract infection: eliminates uropathogens, leading to resolution of urinary symptoms. - Skin and soft‑tissue infection: treats bacterial skin infections, promoting healing and preventing spread. - Complicated intra‑abdominal infection: offers broad‑spectrum activity against mixed flora, supporting clinical recovery.

Levofloxacin may cause a variety of adverse reactions, ranging from mild to severe.

Common Side Effects: - Nausea: mild stomach upset often transient. - Diarrhea: loose stools that may be self‑limiting. - Headache: mild to moderate head pain. - Dizziness: sensation of light‑headedness.

Serious or Rare Side Effects: - Tendon rupture: sudden tendon pain or rupture, especially Achilles. - QT prolongation: cardiac rhythm disturbance that can lead to arrhythmia. - Severe allergic reaction: rash, swelling, breathing difficulty (anaphylaxis).

Before prescribing Levofloxacin, clinicians should consider several safety considerations.

- Assess renal function: dose adjustment may be required in impaired clearance. - Review cardiac history: avoid in patients with known QT prolongation or arrhythmias. - Evaluate tendon risk: caution in patients over 60, on corticosteroids, or with recent tendon injury. - Monitor for hypersensitivity: discontinue if rash, pruritus or anaphylactic signs appear. - Avoid use in pregnancy and lactation unless benefits outweigh risks: safety data are limited. - Store below 25°C: keep in the original pack, protect from moisture.

Levofloxacin can interact with other medicines, altering its efficacy or safety.

Major Interactions (Avoid): - Antacids containing aluminum or magnesium: reduce absorption of levofloxacin. - Warfarin: may increase anticoagulant effect and bleeding risk. - Non‑steroidal anti‑inflammatory drugs (NSAIDs): heightened risk of CNS stimulation and seizures.

Moderate Interactions (Monitor Closely): - Theophylline: levofloxacin can increase serum theophylline levels, requiring monitoring. - Cyclosporine: may raise cyclosporine concentrations, necessitating dose adjustment. - Diabetic agents (e.g., insulin, sulfonylureas): potential for hypoglycemia, monitor blood glucose.