Levofloxacin Actavis

Levofloxacin, the active ingredient in Levofloxacin Actavis, is a fluoroquinolone antibiotic presented as an oral dosage form for systemic use. It treats a range of bacterial infections, including respiratory, urinary, and skin infections, in adult patients. The drug is approved in the European Union and is supplied under a prescription‑only status.

GNH USA supplies Levofloxacin Actavis as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide. Our distribution network ensures reliable delivery to healthcare providers across multiple continents.

Levofloxacin Actavis is a fluoroquinolone antibiotic indicated for several bacterial infection categories. - Community‑acquired respiratory tract infections: effective in eradicating the causative bacteria and improving respiratory symptoms. - Acute bacterial sinusitis: reduces sinus inflammation by eliminating the infecting organisms. - Acute exacerbations of chronic bronchitis: shortens the duration of exacerbation and aids recovery. - Uncomplicated urinary tract infections: clears the infection and relieves urinary symptoms. - Skin and soft tissue infections: treats bacterial skin infections and promotes healing. - Prostatitis: eliminates bacterial pathogens in the prostate and alleviates associated discomfort.

Levofloxacin may cause a range of adverse reactions, varying from mild to severe.

Common Side Effects: - Nausea: mild stomach upset that may resolve without treatment. - Diarrhea: loose stools, sometimes accompanied by abdominal cramping. - Headache: transient head pain that usually improves with rest. - Dizziness: sensation of light‑headedness, especially when standing quickly.

Serious or Rare Side Effects: - Tendon rupture: sudden tendon pain or rupture, most often in the Achilles tendon. - QT interval prolongation: cardiac rhythm changes that can lead to serious arrhythmias. - Severe allergic reaction: rash, swelling, breathing difficulty, or anaphylaxis requiring immediate medical attention.

Before prescribing Levofloxacin, clinicians should consider several safety precautions. - Renal impairment: adjust therapy based on kidney function to avoid drug accumulation. - History of tendon disorders: avoid use in patients with prior tendon inflammation or rupture. - Cardiac risk factors: monitor QT interval in patients with known cardiac arrhythmias or electrolyte disturbances. - Concomitant CNS active drugs: use caution with medications that may lower seizure threshold. - Pregnancy and lactation: assess risk versus benefit, as safety data are limited. - Store at ambient temperature: keep below 25 °C in original packaging, protect from moisture.

Levofloxacin can interact with other medicines, altering its efficacy or safety.

Major Interactions (Avoid): - Antacids containing aluminum or magnesium: reduce levofloxacin absorption; separate dosing by at least 2 hours. - Warfarin: may increase anticoagulant effect, requiring closer INR monitoring. - Non‑steroidal anti‑inflammatory drugs (NSAIDs): increase risk of central nervous system stimulation and seizures.

Moderate Interactions (Monitor Closely): - Theophylline: levofloxacin can raise plasma theophylline levels, necessitating dosage adjustment. - Diabetic agents (e.g., insulin, sulfonylureas): may cause hypoglycemia; monitor blood glucose.