Levofloxacin Accord Healthcare

Levofloxacin, the active ingredient in Levofloxacin Accord Healthcare, is a fluoroquinolone antibiotic presented as an oral tablet for systemic antibacterial use. It treats a variety of bacterial infections in adult patients.

GNH USA supplies Levofloxacin Accord Healthcare as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Levofloxacin is a broad‑spectrum fluoroquinolone used to treat infections caused by susceptible bacteria.

- Community‑acquired pneumonia: eradicates the causative pathogens and improves respiratory symptoms. - Acute bacterial sinusitis: reduces sinus inflammation and clears infection. - Uncomplicated urinary tract infection: eliminates uropathogens and resolves dysuria. - Skin and skin‑structure infections: treats cellulitis, abscesses and wound infections. - Chronic bronchitis exacerbation: shortens illness duration and improves lung function.

Levofloxacin may cause a range of adverse reactions, from mild to severe.

Common Side Effects: - Nausea: mild to moderate gastrointestinal upset. - Diarrhea: loose stools, occasionally watery. - Headache: transient cranial discomfort. - Dizziness: occasional light‑headedness. - Insomnia: difficulty falling or staying asleep. - Rash: mild skin erythema or pruritus.

Serious or Rare Side Effects: - Tendon rupture: especially Achilles, often linked to sudden activity. - QT prolongation: may precipitate cardiac arrhythmias. - Severe hypersensitivity: anaphylaxis or Stevens‑Johnson syndrome. - Central nervous system effects: seizures or psychosis. - Hepatotoxicity: elevated liver enzymes or jaundice. - Clostridioides difficile colitis: severe diarrhea with abdominal pain.

Levofloxacin should be used with caution in specific clinical situations.

- Tendon safety: avoid use in patients with recent tendon injury or steroid therapy. - Cardiac risk: monitor patients with known QT prolongation or electrolyte disturbances. - Renal function: adjust dose in severe renal impairment. - CNS effects: use carefully in patients with a history of seizures. - Pregnancy and lactation: avoid unless clearly needed; safety data are limited. - Store at ambient temperature: keep below 25 °C, retain in original packaging, protect from moisture and direct sunlight.

Levofloxacin can interact with several medicines, altering efficacy or safety.

Major Interactions (Avoid): - Antacids containing aluminum or magnesium: reduce levofloxacin absorption. - Warfarin: may increase anticoagulant effect and bleeding risk. - NSAIDs (e.g., ibuprofen): heighten risk of central nervous system stimulation.

Moderate Interactions (Monitor Closely): - Theophylline: may increase serum theophylline levels, causing toxicity. - Cyclosporine: potential for increased cyclosporine concentrations. - Diabetic agents (e.g., insulin, sulfonylureas): may enhance hypoglycaemic effect.