Europe — EMA
Levofloxacin Accord Healthcare
GNH USA supplies Levofloxacin Accord Healthcare (Levofloxacin), a fluoroquinolone antibiotic for respiratory, urinary and skin infections. Request a quote.
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What is Levofloxacin Hemihydrate?
Levofloxacin, the active ingredient in Levofloxacin Accord Healthcare, is a fluoroquinolone antibiotic presented as an oral tablet for systemic use. It treats a range of bacterial infections in adults and children when prescribed by a qualified health professional.
GNH USA supplies Levofloxacin Accord Healthcare as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.
What is Levofloxacin Hemihydrate used for?
Levofloxacin is a broad‑spectrum antibacterial that targets common bacterial pathogens in several organ systems. - Community‑acquired respiratory tract infections: eradicates susceptible organisms and improves cough, sputum and fever. - Acute bacterial sinusitis: reduces sinus inflammation and clears infection. - Acute exacerbations of chronic bronchitis: shortens symptom duration and prevents complications. - Urinary tract infections: eliminates causative bacteria and relieves dysuria. - Skin and soft‑tissue infections: treats cellulitis, abscesses and other bacterial skin conditions.
What are the side effects of Levofloxacin Hemihydrate?
Levofloxacin may cause a variety of adverse reactions, ranging from mild to severe.
Common Side Effects: - Nausea: mild to moderate gastrointestinal upset. - Diarrhea: loose stools, sometimes watery. - Headache: transient cranial discomfort. - Dizziness: occasional vertigo or light‑headedness. - Rash: mild skin erythema or itching.
Serious or Rare Side Effects: - Tendon rupture: sudden pain and loss of function, especially in the Achilles. - QT prolongation: cardiac rhythm disturbances that may cause palpitations. - Severe allergic reaction: anaphylaxis with swelling, breathing difficulty. - Central nervous system effects: seizures or severe confusion. - Liver injury: jaundice or elevated liver enzymes.
What precautions apply to Levofloxacin Hemihydrate?
Before prescribing Levofloxacin, clinicians should consider several safety factors. - Renal impairment: adjust dose or monitor renal function closely. - History of tendon disorders: avoid use in patients with prior tendon injury. - Cardiac risk: assess QT interval in patients with known arrhythmias. - Pregnancy and lactation: use only if benefits outweigh potential risks, as safety data are limited. - Concomitant CNS active drugs: monitor for increased neurotoxicity. - Store below 25°C: keep in the original container, protect from moisture and heat.
What does Levofloxacin Hemihydrate interact with?
Levofloxacin can interact with other medicines, altering efficacy or safety.
Major Interactions (Avoid): - Antacids containing aluminum or magnesium: markedly reduce levofloxacin absorption. - Warfarin: may increase anticoagulant effect and bleeding risk. - NSAIDs (e.g., ibuprofen): heighten risk of central nervous system stimulation.
Moderate Interactions (Monitor Closely): - Theophylline: may raise serum theophylline levels, requiring dose adjustment. - Corticosteroids: increase risk of tendon rupture. - Diabetic agents: potential for altered glucose control.
Frequently asked questions
What infections is Levofloxacin Accord Healthcare used to treat?+
How does levofloxacin work against bacteria?+
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