Levofloxacin Hikma Farmacêutica (Portugal)

Levofloxacin, the active ingredient in Levofloxacin Hikma Farmacêutica, is a fluoroquinolone antibiotic presented as an injectable solution for intravenous use. It treats a range of serious bacterial infections in adult patients.

GNH USA supplies Levofloxacin Hikma Farmacêutica as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Levofloxacin is a fluoroquinolone antibiotic indicated for several serious bacterial infections.

Community‑acquired pneumonia: achieves clinical cure and bacterial eradication in adults. Complicated urinary tract infections: resolves infection and prevents recurrence. Complicated intra‑abdominal infections: provides effective bacterial clearance. Skin and soft‑tissue infections: reduces lesion size and promotes healing. Prostatitis: eliminates causative pathogens and improves symptoms.

Levofloxacin may cause a variety of adverse reactions, ranging from mild to severe.

Common Side Effects: - Nausea: mild to moderate gastrointestinal upset. - Diarrhea: loose stools, sometimes watery. - Headache: transient cranial discomfort. - Dizziness: sensation of light‑headedness. - Rash: mild skin erythema or pruritus. - Elevated liver enzymes: transient increase in hepatic transaminases.

Serious or Rare Side Effects: - Tendon rupture: especially Achilles tendon, may occur without warning. - QT interval prolongation: risk of cardiac arrhythmias. - Severe allergic reactions: anaphylaxis, angioedema. - Clostridioides difficile infection: colitis with profuse diarrhea. - Hepatic failure: rare but potentially life‑threatening liver injury. - Seizures: especially in patients with CNS disorders or electrolyte imbalance.

Levofloxacin requires careful consideration of patient‑specific factors before use.

Renal impairment: adjust dose based on renal function. History of tendon disorders: avoid use due to risk of rupture. Concomitant QT‑prolonging drugs: monitor ECG and electrolytes. Pregnancy Category C: prescribe only if benefits outweigh potential risks. Hypersensitivity: discontinue immediately if allergic reaction occurs. Store at 2‑8 °C: keep refrigerated, protect from light, do not freeze.

Levofloxacin can interact with several medicines, affecting safety or efficacy.

Major Interactions (Avoid): - Antacids or supplements containing magnesium, aluminum, calcium, or iron: markedly reduce levofloxacin absorption. - Warfarin: may enhance anticoagulant effect and increase bleeding risk. - Other fluoroquinolones: combined use increases toxicity without added benefit.

Moderate Interactions (Monitor Closely): - NSAIDs: may increase risk of central nervous system stimulation. - Corticosteroids: concurrent use raises the chance of tendon rupture.