Levofloxacin 1 A Pharma

Levofloxacin, the active ingredient in Levofloxacin 1 A Pharma, is a fluoroquinolone antibiotic presented as an oral dosage form for oral use. It treats a range of bacterial infections in adults and adolescents as prescribed by a healthcare professional.

GNH USA supplies Levofloxacin 1 A Pharma as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Levofloxacin is indicated for several bacterial infections affecting the respiratory, urinary and skin systems.

- Community‑acquired bacterial pneumonia: effective treatment of the infection in adults. - Acute bacterial sinusitis: rapid resolution of sinus inflammation caused by susceptible organisms. - Acute exacerbations of chronic bronchitis: helps reduce symptoms and prevent further lung damage. - Uncomplicated urinary tract infections: eradicates common uropathogens. - Skin and soft tissue infections: clears infection in cutaneous lesions caused by susceptible bacteria.

Levofloxacin may cause a range of adverse reactions, varying from mild to severe.

Common Side Effects: - Nausea: mild to moderate upset stomach. - Diarrhea: loose stools, sometimes watery. - Headache: transient cranial discomfort. - Dizziness: sensation of light‑headedness.

Serious or Rare Side Effects: - Tendon rupture: sudden pain and loss of function, especially in the Achilles. - QT interval prolongation: risk of cardiac arrhythmias. - Severe allergic reactions: rash, swelling, or anaphylaxis. - Clostridioides difficile infection: severe colitis after antibiotic use. - Peripheral neuropathy: numbness or tingling in extremities.

Levofloxacin should be used with caution in specific clinical situations.

- Renal function assessment: dose adjustment may be required in impaired kidneys. - Hypersensitivity: avoid in patients with known allergy to fluoroquinolones. - Elderly patients: monitor for CNS effects such as confusion or seizures. - Concomitant corticosteroid therapy: increased risk of tendon injury. - Tendon pain or inflammation: discontinue use and seek medical advice. - Store at room temperature: keep in the original pack, protect from moisture.

Levofloxacin can interact with several medicines, altering efficacy or safety.

Major Interactions (Avoid): - Antacids containing magnesium or aluminum: reduce levofloxacin absorption. - Warfarin: may increase INR and bleeding risk. - Theophylline: elevated plasma levels can cause toxicity.

Moderate Interactions (Monitor Closely): - Corticosteroids: heightened risk of tendon rupture. - Drugs that prolong QT interval: additive cardiac risk. - CYP1A2 substrates (e.g., caffeine): possible increased concentrations.