GNH USA

Europe — EMA

Levoflox

GNH USA supplies Levoflox (Levofloxacin), a fluoroquinolone antibiotic for urinary tract infections, community‑acquired pneumonia, and other bacterial

Levofloxacin Hemihydrate

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What is Levofloxacin Hemihydrate?

Levofloxacin, the active ingredient in Levoflox, is a fluoroquinolone antibiotic presented as an oral tablet for systemic use. It treats a range of bacterial infections in adults and children when prescribed by a healthcare professional. GNH USA supplies Levoflox as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

What is Levofloxacin Hemihydrate used for?

Levoflox is a fluoroquinolone antibacterial used to treat infections caused by susceptible bacteria. - Urinary tract infections: eradicates the causative organisms and resolves urinary symptoms. - Community‑acquired pneumonia: eliminates pulmonary pathogens to improve respiratory function. - Acute bacterial sinusitis: clears sinus infection and reduces congestion. - Skin and soft tissue infections: combats bacterial invasion of skin layers. - Complicated intra‑abdominal infections: targets mixed bacterial flora to aid recovery.

What are the side effects of Levofloxacin Hemihydrate?

Levoflox may cause a range of adverse reactions, from mild to severe.

Common Side Effects: - Nausea: mild stomach upset often occurring after dosing. - Diarrhea: loose stools that may be self‑limiting. - Headache: transient cranial discomfort. - Dizziness: sensation of light‑headedness or unsteadiness. - Insomnia: difficulty falling or staying asleep.

Serious or Rare Side Effects: - Tendon rupture: sudden tendon pain or loss of function, especially in the Achilles. - QT interval prolongation: potential cardiac arrhythmias requiring monitoring. - Clostridioides difficile infection: severe colitis with watery diarrhea. - Severe allergic reactions: rash, swelling, or anaphylaxis. - Peripheral neuropathy: numbness or tingling in extremities.

What precautions apply to Levofloxacin Hemihydrate?

Before prescribing Levoflox, clinicians should consider several safety factors. - Assess renal function: adjust dosing in patients with impaired clearance. - Avoid in patients with known tendon disorders: increased risk of tendon rupture. - Monitor QT interval: may prolong cardiac repolarization in susceptible individuals. - Use with caution in pregnancy: safety category is unknown, weigh benefits against risks. - Store at ambient temperature: keep in the original pack, protect from moisture.

What does Levofloxacin Hemihydrate interact with?

Levoflox can interact with other medicines, altering its effectiveness or safety.

Major Interactions (Avoid): - Antacids containing aluminum or magnesium: markedly reduce levofloxacin absorption. - Warfarin: may enhance anticoagulant effect and increase bleeding risk. - Cyclosporine: can raise levofloxacin plasma concentrations, leading to toxicity.

Moderate Interactions (Monitor Closely): - Theophylline: levofloxacin may increase serum theophylline levels, risking toxicity. - Corticosteroids: combined use raises the chance of tendon injury. - NSAIDs: may potentiate central nervous system side effects such as seizures.

Frequently asked questions

What infections is Levoflox used to treat?+
Levoflox is indicated for several bacterial infections, including uncomplicated urinary tract infections, community‑acquired pneumonia, acute bacterial sinusitis, skin and soft‑tissue infections, and complicated intra‑abdominal infections caused by susceptible organisms.
How does levofloxacin work to fight bacteria?+
Levofloxacin blocks bacterial DNA gyrase and topoisomerase IV, enzymes required for DNA replication and transcription. This inhibition prevents bacterial cells from multiplying, leading to their death and resolution of the infection.
What is the usual dose of Levoflox?+
The dosage of Levoflox is determined by the prescribing clinician based on the specific infection, patient age, kidney function, and other clinical factors. Patients should follow the exact regimen provided by their healthcare professional.
Is Levoflox safe to use during pregnancy or breastfeeding?+
Levoflox falls into an unknown pregnancy category, and its safety for the fetus or nursing infant has not been established. Healthcare providers should weigh potential benefits against possible risks before prescribing it to pregnant or lactating women.
How do I order Levoflox from GNH USA?+
To request Levoflox, submit an enquiry on the product page at gnh-usa.com specifying the required quantity. GNH USA works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.
How does Levoflox compare with other fluoroquinolones?+
Levoflox (levofloxacin) is a third‑generation fluoroquinolone with a broad spectrum of activity against Gram‑negative and Gram‑positive bacteria. Compared with older agents like ciprofloxacin, it often requires once‑daily dosing and may achieve higher tissue concentrations, but the safety profile and resistance considerations remain similar across the class.
What are the recommended storage conditions for Levoflox?+
Levoflox tablets should be stored at ambient temperature, below 25 °C, in the original packaging to protect them from moisture and light. Keep the container tightly closed and out of reach of children.
How is Levoflox administered to patients?+
Levoflox is taken orally, usually with a full glass of water. It can be taken with or without food, but antacids containing aluminum or magnesium should be avoided within two hours of dosing to ensure proper absorption.
What are the most serious risks associated with Levoflox?+
Serious risks include tendon rupture (especially the Achilles tendon), QT interval prolongation leading to cardiac arrhythmias, severe allergic reactions such as anaphylaxis, Clostridioides difficile‑associated colitis, and peripheral neuropathy. Patients should seek immediate medical attention if they experience any of these symptoms.
Who should not take Levoflox?+
Levoflox is contraindicated in individuals with a known hypersensitivity to levofloxacin, other fluoroquinolones, or any component of the formulation. It should also be avoided in patients with a history of tendon disorders related to fluoroquinolone use.
Information provided on this page is for educational use by procurement and clinical professionals. Always consult a licensed healthcare provider for medical advice and prescribing decisions. GNH USA supplies this product subject to applicable regulatory and licensing requirements.

Product details

Drug
Levofloxacin Hemihydrate
Route
Oral Use
Manufacturer
Hec Pharm Gmbh
Origin
EU

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