Levofloksacin Lek

Levofloxacin, the active ingredient in Levofloksacin Lek, is a fluoroquinolone antibiotic presented as a tablet for oral use. It treats susceptible bacterial infections in adults and children when prescribed by a healthcare professional. GNH USA supplies Levofloksacin Lek as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Levofloxacin is a broad‑spectrum antibacterial that targets a range of bacterial pathogens in various infection sites.

- Community‑acquired pneumonia: eradicates susceptible organisms causing lung infection. - Acute bacterial sinusitis: reduces bacterial load in sinus cavities. - Acute exacerbation of chronic bronchitis: improves respiratory symptoms by eliminating pathogens. - Uncomplicated urinary tract infection: clears infection in the urinary tract. - Skin and soft‑tissue infections: treats susceptible Gram‑positive and Gram‑negative bacteria.

Levofloxacin may cause a range of adverse reactions, from mild to severe.

Common Side Effects: - Nausea: mild to moderate stomach upset. - Diarrhea: loose stools, sometimes watery. - Headache: transient cranial discomfort. - Dizziness: sensation of light‑headedness. - Insomnia: difficulty falling or staying asleep. - Abdominal pain: cramping or discomfort.

Serious or Rare Side Effects: - Tendon rupture: sudden pain, swelling, or loss of function. - QT interval prolongation: risk of cardiac arrhythmias. - Severe allergic reactions: rash, swelling, anaphylaxis. - Clostridioides difficile infection: severe colitis. - Peripheral neuropathy: numbness or tingling. - Stevens‑Johnson syndrome: severe skin and mucous membrane reactions.

Levofloxacin requires careful consideration of patient factors and proper handling. - Assess renal function: adjust dosing in impaired kidney function. - Avoid in patients with known fluoroquinolone hypersensitivity: risk of severe reactions. - Monitor for tendon pain: discontinue if signs of tendonitis or rupture appear. - Use caution in patients with QT prolongation risk: avoid concomitant QT‑prolonging drugs. - Avoid concomitant antacids containing magnesium or aluminum: may reduce absorption. - Store at room temperature: keep in original container, protect from moisture and light.

Levofloxacin can interact with several medicines, affecting safety or efficacy.

Major Interactions (Avoid): - Warfarin: increased anticoagulant effect, risk of bleeding. - Theophylline: elevated serum levels, potential toxicity. - NSAIDs (e.g., ibuprofen): reduced levofloxacin absorption and increased GI risk.

Moderate Interactions (Monitor Closely): - Antacids containing magnesium/aluminum: may decrease levofloxacin bioavailability. - Iron supplements: can reduce drug absorption. - Corticosteroids: heightened risk of tendon rupture; monitor musculoskeletal symptoms.