Levofloksacin Kabi

Levofloxacin, the active ingredient in Levofloksacin Kabi, is a fluoroquinolone presented as an intravenous formulation for systemic use. It treats a range of bacterial infections in adult patients, including respiratory, urinary, intra‑abdominal and skin infections.

GNH USA supplies Levofloksacin Kabi as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals worldwide.

Levofloxacin is a broad‑spectrum fluoroquinolone antibiotic used to treat serious bacterial infections across several organ systems.

Community‑acquired pneumonia: effective against typical respiratory pathogens, improving clinical recovery. Complicated urinary tract infections: eradicates resistant Gram‑negative organisms in the urinary tract. Complicated intra‑abdominal infections: targets mixed aerobic and anaerobic bacteria. Skin and soft tissue infections: covers common skin pathogens including Staphylococcus aureus. Acute bacterial sinusitis: reduces bacterial load and alleviates sinus inflammation.

Levofloxacin may cause a variety of adverse reactions, ranging from mild to severe.

Common Side Effects: - Nausea - Diarrhea - Headache - Dizziness - Rash - Elevated liver enzymes

Serious or Rare Side Effects: - Tendon rupture or tendinitis - QT interval prolongation - Severe allergic reactions (anaphylaxis, Stevens‑Johnson syndrome) - Clostridioides difficile‑associated diarrhea - Peripheral neuropathy - Hepatotoxicity

Levofloxacin requires careful consideration of patient‑specific factors before use.

Assess renal function: adjust dosing in patients with impaired clearance. Monitor for tendon pain: discontinue if signs of tendinitis or rupture appear. Avoid in patients with known hypersensitivity to fluoroquinolones. Use caution in the elderly: higher risk of central nervous system effects. Avoid concomitant use with other QT‑prolonging agents. Store at controlled room temperature: keep in the original container, protect from light and moisture.

Levofloxacin can interact with several medicines, altering efficacy or safety.

Major Interactions (Avoid): - Antacids containing magnesium or aluminum: reduce levofloxacin absorption. - Warfarin: may increase anticoagulant effect and bleeding risk. - Theophylline: increased plasma concentrations leading to toxicity. - Corticosteroids: heightened risk of tendon rupture. - Cyclosporine: elevated levofloxacin levels, increasing adverse effects.

Moderate Interactions (Monitor Closely): - NSAIDs: additive risk of central nervous system stimulation. - Diabetes medications: potential impact on glucose control. - Benzodiazepines: may enhance sedative effects.