GNH USA

Europe — EMA

Levodopa/Benserazid Devatis (Benserazide, Levodopa)

GNH USA supplies Levodopa/Benserazid Devatis (Levodopa/Benserazide), a antiparkinson agent for Parkinson's disease treatment. Request a quote for supply.

Benserazide, Levodopa

Request sourcing

1
Pack/s

What is Benserazide, Levodopa?

Levodopa, the active ingredient in Levodopa/Benserazid Devatis, is an antiparkinson agent presented as an oral tablet for oral use. It is combined with benserazide to treat Parkinson's disease in adult patients by restoring central dopamine levels. Levodopa is a precursor of dopamine that crosses the blood‑brain barrier, while benserazide limits peripheral conversion, enhancing therapeutic effect and reducing side effects.

GNH USA supplies Levodopa/Benserazid Devatis as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide. The company adheres to stringent quality standards and provides regulatory‑approved batches for global distribution.

What is Benserazide, Levodopa used for?

Levodopa/Benserazide is used in the management of Parkinsonian disorders, targeting dopaminergic deficiency. - Parkinson's disease: reduces rigidity, tremor and bradykinesia. - Resting tremor: alleviates tremor episodes. - Motor fluctuations in Parkinson's disease: smooths out on/off periods.

What are the side effects of Benserazide, Levodopa?

Adverse reactions may occur with levodopa/benserazide therapy.

Common Side Effects: - Nausea - Orthostatic hypotension - Dizziness - Insomnia

Serious or Rare Side Effects: - Dyskinesia (involuntary movements) - Hallucinations or psychosis - Severe hypotension

What precautions apply to Benserazide, Levodopa?

Careful monitoring and patient education are essential when using levodopa/benserazide. - Dose titration: start low and increase gradually to minimize side effects. - Monitor blood pressure: risk of orthostatic hypotension. - Assess for psychiatric symptoms: watch for hallucinations or psychosis. - Avoid abrupt discontinuation: may cause withdrawal phenomena. - Store at ambient temperature: keep in the original container, protect from moisture and light.

What does Benserazide, Levodopa interact with?

Levodopa/benserazide can interact with several drug classes.

Major Interactions (Avoid): - Non‑selective MAO inhibitors: risk of hypertensive crisis. - Anticholinergic drugs: may reduce levodopa efficacy. - High‑protein meals: compete for transport, decreasing absorption.

Moderate Interactions (Monitor Closely): - Antidepressants (SSRIs, SNRIs): may increase risk of serotonin syndrome. - Iron or calcium supplements: can bind levodopa, reducing absorption.

Frequently asked questions

What is Levodopa/Benserazid Devatis used for?+
Levodopa/Benserazid Devatis is prescribed to manage the motor symptoms of Parkinson's disease. It combines levodopa, a dopamine precursor, with benserazide, an inhibitor that enhances central availability, helping to improve tremor, rigidity, and bradykinesia in adult patients.
How does levodopa work in the body?+
Levodopa is absorbed from the gastrointestinal tract and crosses the blood‑brain barrier, where it is converted into dopamine by aromatic L‑amino acid decarboxylase. The added benserazide blocks this conversion in peripheral tissues, allowing more levodopa to reach the brain and restore dopaminergic neurotransmission.
What is the usual dose of Levodopa/Benserazid Devatis?+
The specific dose and dosing schedule are determined by the prescribing clinician based on the individual’s disease severity, response, and tolerability. Physicians typically start with a low dose and titrate upward to achieve optimal symptom control while minimizing side effects.
Is Levodopa/Benserazid Devatis safe during pregnancy or breastfeeding?+
Safety data for use in pregnancy and lactation are limited, and the product is classified as having an unknown pregnancy category. Healthcare providers should weigh potential benefits against risks and consider alternative therapies when treating pregnant or nursing individuals.
How do I order Levodopa/Benserazid Devatis from GNH USA?+
To place an order, submit an enquiry on the product page at gnh-usa.com specifying the required quantity. GNH USA works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details, and any necessary import documentation.
How does Levodopa/Benserazid Devatis compare with other Parkinson’s drugs?+
Levodopa/benserazide is considered the most effective symptomatic therapy for Parkinson’s disease because it directly replenishes dopamine. Compared with dopamine agonists, it often provides stronger motor improvement but may have a higher risk of motor complications such as dyskinesia over long‑term use.
What are the storage requirements for Levodopa/Benserazid Devatis?+
Store the product at ambient temperature, preferably below 25 °C. Keep it in the original packaging, protect it from moisture and direct light, and ensure the container is tightly closed to maintain stability throughout its shelf life.
How is Levodopa/Benserazid Devatis administered?+
The medication is taken orally, usually with a glass of water. It may be taken with or without food, but high‑protein meals can interfere with absorption, so clinicians often advise spacing the dose away from protein‑rich foods.
What are the most serious risks associated with Levodopa/Benserazid Devatis?+
Serious risks include the development of dyskinesia (involuntary movements), psychiatric disturbances such as hallucinations or psychosis, and severe orthostatic hypotension. Patients should be monitored regularly for these events, and any sudden changes should be reported to a healthcare professional.
Who should not use Levodopa/Benserazid Devatis?+
Individuals with known hypersensitivity to levodopa, benserazide, or any excipients should avoid the product. It is also contraindicated in patients taking non‑selective MAO inhibitors and those with narrow‑angle glaucoma or severe cardiovascular disease without careful medical supervision.
Information provided on this page is for educational use by procurement and clinical professionals. Always consult a licensed healthcare provider for medical advice and prescribing decisions. GNH USA supplies this product subject to applicable regulatory and licensing requirements.
Send a sourcing enquiry for this product →

Product details

Drug
Benserazide, Levodopa
Route
Oral Use
Manufacturer
Devatis Gmbh
Origin
EU

Related products

Levobens

Levobens

Benserazide, Levodopa

Teva Gmbh
EU
Levodopa Benserazid Beta

Levodopa Benserazid Beta

Benserazide, Levodopa

Betapharm Arzneimittel Gmbh
EU
Levodopa Benserazide Teva

Levodopa Benserazide Teva

Benserazide, Levodopa

Teva Santé
EU
Levodopa Plus Benserazid Al

Levodopa Plus Benserazid Al

Benserazide, Levodopa

Aliud Pharma Gmbh
EU