GNH USA

Europe — EMA

Levocetirizine Dihydrochloride Aurobindo

GNH USA supplies Levocetirizine Dihydrochloride (Levocetirizine), a antihistamine for allergic rhinitis and chronic idiopathic urticaria.

Levocetirizine Dihydrochloride

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What is Levocetirizine Dihydrochloride?

Levocetirizine dihydrochloride, the active ingredient in Levocetirizine Dihydrochloride Aurobindo, is an antihistamine presented as a tablet for oral use. It is used to relieve symptoms of allergic rhinitis and chronic idiopathic urticaria in adults and children.

GNH USA supplies Levocetirizine Dihydrochloride Aurobindo as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide, ensuring consistent quality and regulatory compliance across markets.

What is Levocetirizine Dihydrochloride used for?

Levocetirizine dihydrochloride acts on histamine‑mediated allergic pathways and is indicated for the following conditions: - Allergic rhinitis: reduces sneezing, nasal itching, rhinorrhea and congestion. - Chronic idiopathic urticaria: alleviates hives and associated itching. - Seasonal allergic rhinitis: controls symptoms triggered by pollen exposure.

What are the side effects of Levocetirizine Dihydrochloride?

Levocetirizine dihydrochloride is generally well tolerated, but adverse reactions can occur.

Common Side Effects: - Drowsiness: mild to moderate sedation. - Dry mouth: reduced salivation. - Headache: transient cranial discomfort. - Fatigue: feeling of tiredness. - Nausea: mild gastrointestinal upset. - Altered taste: temporary metallic or bitter sensation.

Serious or Rare Side Effects: - Angioedema: swelling of face, lips or tongue. - Severe skin reactions: such as Stevens‑Johnson syndrome. - Anaphylaxis: acute, life‑threatening allergic response. - Tachycardia: rapid heart rate. - Hepatic dysfunction: abnormal liver enzymes. - Blood dyscrasias: rare hematologic abnormalities.

What precautions apply to Levocetirizine Dihydrochloride?

When using Levocetirizine dihydrochloride, consider the following precautions: - Pregnancy: consult a healthcare provider before use. - Breastfeeding: assess risk versus benefit with a clinician. - Renal impairment: dose may require adjustment in reduced kidney function. - Elderly patients: monitor for increased sedation. - Driving or operating machinery: avoid if drowsiness occurs. - Store at room temperature: keep in the original container, protect from moisture and light.

What does Levocetirizine Dihydrochloride interact with?

Levocetirizine dihydrochloride may interact with other medicines. Review the following categories:

Major Interactions (Avoid): - Alcohol: can enhance sedative effects. - Central nervous system depressants (e.g., benzodiazepines): additive drowsiness. - Strong CYP3A4 inhibitors (e.g., ketoconazole, erythromycin): may raise plasma concentrations.

Moderate Interactions (Monitor Closely): - Theophylline: levocetirizine may increase its clearance. - Ritonavir: may elevate levocetirizine exposure. - Anticholinergic agents: may worsen dry‑mouth symptoms.

Frequently asked questions

What is Levocetirizine Dihydrochloride used for?+
Levocetirizine Dihydrochloride is an antihistamine indicated for the relief of symptoms associated with allergic rhinitis and chronic idiopathic urticaria, helping to reduce sneezing, itching, nasal discharge, and hives.
How does levocetirizine work?+
Levocetirizine works by selectively blocking peripheral H1 histamine receptors, preventing histamine from triggering the cascade that leads to allergy symptoms such as vasodilation, increased vascular permeability, and sensory nerve activation.
What is the usual dose of levocetirizine?+
The appropriate dose of levocetirizine is determined by the prescribing healthcare professional based on the patient’s age, condition severity, renal function and other individual factors.
Is levocetirizine safe during pregnancy or breastfeeding?+
Safety in pregnancy and lactation has not been fully established. Women who are pregnant, planning to become pregnant, or breastfeeding should discuss potential risks and benefits with their healthcare provider before using levocetirizine.
How do I order Levocetirizine Dihydrochloride from GNH USA?+
To place an order, submit an enquiry on the product page at gnh-usa.com specifying the required quantity. GNH USA works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.
How does levocetirizine compare with other antihistamines?+
Levocetirizine is the active enantiomer of cetirizine, offering similar efficacy with a potentially lower incidence of sedation. Compared with first‑generation antihistamines, it provides better selectivity for H1 receptors and fewer anticholinergic side effects.
What are the storage requirements for Levocetirizine Dihydrochloride?+
Store the product at room temperature, below 25 °C, in its original packaging. Keep it away from moisture, direct sunlight and excessive heat to maintain stability.
How is Levocetirizine Dihydrochloride administered?+
Levocetirizine Dihydrochloride is taken orally, usually as a tablet, with or without food, as directed by a healthcare professional.
What are the most serious risks associated with levocetirizine?+
Serious but rare risks include angioedema, severe skin reactions such as Stevens‑Johnson syndrome, and anaphylaxis. Patients should seek immediate medical attention if they experience swelling of the face or throat, rash, or difficulty breathing.
Who should not use levocetirizine?+
Levocetirizine should be avoided in individuals with known hypersensitivity to the drug or any of its excipients. Caution is also advised for patients with severe renal impairment, unless dose adjustments are made by a physician.
Information provided on this page is for educational use by procurement and clinical professionals. Always consult a licensed healthcare provider for medical advice and prescribing decisions. GNH USA supplies this product subject to applicable regulatory and licensing requirements.

Product details

Drug
Levocetirizine Dihydrochloride
Route
Oral Use
Manufacturer
Aurobindo Pharma B.V.
Origin
EU

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