GNH USA

Europe — EMA

Levocetirizine Dihydrochloride Activase Pharmaceuticals

GNH USA supplies Levocetirizine Dihydrochloride (Levocetirizine), an antihistamine for allergic rhinitis and urticaria. Request a quote for global supply.

Levocetirizine Dihydrochloride

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What is Levocetirizine Dihydrochloride?

Levocetirizine dihydrochloride, the active ingredient in Levocetirizine Dihydrochloride Activase Pharmaceuticals, is an antihistamine presented as an oral tablet for oral use. It treats allergic rhinitis and chronic idiopathic urticaria in adults and children.

GNH USA supplies Levocetirizine Dihydrochloride Activase Pharmaceuticals as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide. The product conforms to EU quality standards and is manufactured under GMP conditions. Our global network ensures reliable delivery to diverse healthcare settings.

What is Levocetirizine Dihydrochloride used for?

Levocetirizine dihydrochloride is used to manage allergic conditions by blocking peripheral H1 receptors.

- Allergic rhinitis: reduces nasal congestion, sneezing, itching and watery discharge. - Seasonal allergic rhinitis: alleviates symptoms triggered by pollen exposure. - Chronic idiopathic urticaria: decreases hives and associated itching.

What are the side effects of Levocetirizine Dihydrochloride?

Adverse reactions to levocetirizine dihydrochloride vary in frequency and severity.

Common Side Effects: - Drowsiness: mild to moderate sedation. - Headache: transient cranial discomfort. - Dry mouth: reduced salivation. - Fatigue: general tiredness. - Nausea: occasional stomach upset. - Dizziness: light‑headed sensation.

Serious or Rare Side Effects: - Angioedema: swelling of face, lips or tongue. - Anaphylaxis: severe, life‑threatening allergic reaction. - Stevens‑Johnson syndrome: severe skin eruption. - Hepatic enzyme elevation: abnormal liver function tests. - Blood dyscrasias: rare hematologic abnormalities.

What precautions apply to Levocetirizine Dihydrochloride?

When prescribing levocetirizine dihydrochloride, several safety considerations should be observed.

- Pregnancy: consult a healthcare professional before use. - Breastfeeding: assess risk versus benefit for the infant. - Renal impairment: dose may require adjustment in reduced kidney function. - Elderly patients: monitor for increased sedation or confusion. - Alcohol consumption: avoid or limit as it may enhance drowsiness. - Store at ambient temperature: keep in the original container, protect from moisture.

What does Levocetirizine Dihydrochloride interact with?

Levocetirizine dihydrochloride can interact with other medicines, influencing its efficacy or safety.

Major Interactions (Avoid): - Ketoconazole: may increase levocetirizine plasma concentrations. - Erythromycin: can raise systemic exposure. - Ritonavir: may elevate drug levels significantly.

Moderate Interactions (Monitor Closely): - Alcohol: additive central nervous system depression. - Other antihistamines: potential for excessive sedation. - Theophylline: may reduce theophylline clearance, requiring monitoring.

Frequently asked questions

What conditions is Levocetirizine Dihydrochloride used for?+
Levocetirizine Dihydrochloride is indicated for the relief of symptoms associated with allergic rhinitis, including seasonal and perennial forms, and for the treatment of chronic idiopathic urticaria, helping to reduce hives and itching.
How does levocetirizine work in the body?+
The drug acts as a selective peripheral H1‑receptor antagonist. By blocking histamine binding at these receptors, it prevents the cascade that leads to vasodilation, increased vascular permeability, and sensory nerve activation, thereby reducing typical allergic signs such as itching, swelling, and nasal congestion.
What is the usual dose of levocetirizine?+
The appropriate dose is determined by the prescribing healthcare professional based on the patient’s age, condition severity, renal function and other clinical factors. Patients should follow the prescriber’s instructions and not alter the dose without medical advice.
Is levocetirizine safe during pregnancy or breastfeeding?+
Safety data are limited; therefore, use during pregnancy or while breastfeeding should only occur if the potential benefit justifies the potential risk. Healthcare providers should evaluate each case individually and discuss possible alternatives.
How do I order Levocetirizine Dihydrochloride from GNH USA?+
Enquiries are submitted via the product page on gnh-usa.com, where you specify the required quantity. GNH USA works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.
How does levocetirizine compare with other antihistamines?+
Levocetirizine is the active enantiomer of cetirizine, offering similar efficacy with a potentially lower incidence of sedation. Compared with first‑generation antihistamines, it has a more favorable safety profile and does not readily cross the blood‑brain barrier, reducing central nervous system effects.
What are the recommended storage conditions for this product?+
Store the oral tablets at ambient temperature, below 25 °C, in the original packaging. Keep the container tightly closed, protect it from moisture and direct sunlight to maintain product stability.
How is levocetirizine administered?+
Levocetirizine is taken orally, usually as a tablet, with or without food. The tablet should be swallowed whole with a glass of water. Patients should not crush, chew, or split the tablet unless specifically instructed by a healthcare professional.
What are the most serious risks associated with levocetirizine?+
Serious adverse reactions, although rare, include angioedema, anaphylaxis, severe skin reactions such as Stevens‑Johnson syndrome, and significant hepatic enzyme elevations. Any signs of swelling, rash, or difficulty breathing require immediate medical attention.
Who should not use levocetirizine?+
Individuals with known hypersensitivity to levocetirizine, cetirizine or any excipients in the formulation should avoid the drug. Caution is also advised for patients with severe renal impairment, as dose adjustment may be necessary, and for those taking interacting medications listed under major interactions.
Information provided on this page is for educational use by procurement and clinical professionals. Always consult a licensed healthcare provider for medical advice and prescribing decisions. GNH USA supplies this product subject to applicable regulatory and licensing requirements.
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Product details

Drug
Levocetirizine Dihydrochloride
Route
Oral Use
Manufacturer
Activase Pharmaceuticals Limited
Origin
EU

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