GNH USA

Europe — EMA

Levocetirizine Dihcl Pch

GNH USA supplies Levocetirizine Dihcl Pch (Levocetirizine), a second-generation antihistamine for allergic rhinitis and chronic idiopathic urticaria.

Levocetirizine Dihydrochloride

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What is Levocetirizine Dihydrochloride?

Levocetirizine dihydrochloride, the active ingredient in Levocetirizine Dihcl Pch, is a second-generation antihistamine presented as an oral tablet for oral use. It treats allergic rhinitis and chronic idiopathic urticaria in adults and children.

GNH USA supplies Levocetirizine Dihcl Pch as a licensed, GDP-compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

What is Levocetirizine Dihydrochloride used for?

Levocetirizine is a second‑generation H1‑antihistamine that alleviates allergic airway and skin conditions.

- Allergic rhinitis (seasonal): reduces sneezing, nasal congestion, itching and rhinorrhea. - Allergic rhinitis (perennial): improves persistent nasal symptoms and eye irritation. - Chronic idiopathic urticaria: diminishes hives, itching and associated discomfort.

What are the side effects of Levocetirizine Dihydrochloride?

Levocetirizine is generally well tolerated, but adverse reactions can occur.

Common Side Effects: - Drowsiness or mild sedation - Headache - Dry mouth - Fatigue - Nausea - Altered taste perception

Serious or Rare Side Effects: - Angioedema or severe swelling - Anaphylactic reactions - Stevens‑Johnson syndrome or severe skin rash - Hepatic enzyme elevation - Thrombocytopenia - Cardiac arrhythmias (rare)

What precautions apply to Levocetirizine Dihydrochloride?

Before using Levocetirizine, consider the following safety measures.

- Pregnancy: consult a healthcare professional; use only if benefits outweigh risks. - Breastfeeding: caution advised; monitor infant for sedation. - Renal impairment: dose may need adjustment in reduced kidney function. - Elderly patients: monitor for increased sedation or confusion. - Drug interactions: avoid concomitant use with other CNS depressants or antihistamines. - Store at ambient temperature: keep in the original pack, protect from moisture and direct sunlight.

What does Levocetirizine Dihydrochloride interact with?

Levocetirizine may interact with several medicines; categorize them as follows.

Major Interactions (Avoid): - Alcohol or other CNS depressants - Other antihistamines (e.g., diphenhydramine) - Ritonavir (strong CYP3A4 inhibitor) - Ketoconazole (potent CYP3A4 inhibitor) - Erythromycin (CYP3A4 substrate inhibitor)

Moderate Interactions (Monitor Closely): - Cimetidine (may increase plasma levels) - Theophylline (possible increased side effects) - Fluoroquinolones (potential additive CNS effects) - Phenobarbital (enzyme inducer, may reduce efficacy) - Warfarin (monitor INR as occasional interaction reported)

Frequently asked questions

What conditions is Levocetirizine Dihcl Pch used for?+
Levocetirizine Dihcl Pch is indicated for the relief of symptoms associated with allergic rhinitis—including sneezing, nasal congestion, itching and watery discharge—and for the management of chronic idiopathic urticaria, where it reduces hives and itching.
How does Levocetirizine work in the body?+
Levocetirizine selectively antagonizes peripheral histamine H1 receptors. By blocking these receptors, it prevents histamine‑mediated vasodilation, increased vascular permeability, and sensory nerve activation, thereby reducing the inflammatory and itching responses characteristic of allergic conditions.
What is the usual dose of Levocetirizine Dihcl Pch?+
The appropriate dose is determined by the prescribing clinician based on the patient’s age, severity of symptoms, and renal function. Typically, an oral tablet is taken once daily, but the exact regimen should follow the prescriber’s instructions.
Is Levocetirizine safe during pregnancy or breastfeeding?+
Safety data in pregnancy and lactation are limited. Levocetirizine should only be used if the potential benefit justifies any possible risk to the fetus or infant, and this decision should be made in consultation with a qualified healthcare professional.
How do I order Levocetirizine Dihcl Pch from GNH USA?+
To place an order, submit an enquiry on the product page at gnh-usa.com, specifying the required quantity. GNH USA works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.
How does Levocetirizine compare with other antihistamines?+
Levocetirizine is a second‑generation antihistamine offering effective symptom control with a lower incidence of sedation compared with first‑generation agents such as diphenhydramine. It provides a rapid onset of action and is often preferred for patients who need daytime symptom relief without significant drowsiness.
What are the storage and handling requirements for Levocetirizine Dihcl Pch?+
Store the product at ambient temperature, preferably below 25 °C. Keep the tablets in their original packaging, protect them from moisture and direct sunlight, and ensure the container is tightly closed to maintain product stability.
How is Levocetirizine Dihcl Pch administered?+
Levocetirizine is taken orally as a tablet. Swallow the tablet whole with a glass of water; it may be taken with or without food, according to the prescriber’s guidance.
What are the most serious risks associated with Levocetirizine?+
Although rare, serious adverse reactions can include angioedema, severe skin reactions such as Stevens‑Johnson syndrome, anaphylaxis, hepatic enzyme elevations, and, in exceptional cases, cardiac arrhythmias. Patients should seek immediate medical attention if they experience swelling of the face, lips, tongue, or difficulty breathing.
Who should avoid using Levocetirizine Dihcl Pch?+
Levocetirizine should not be used by individuals with a known hypersensitivity to levocetirizine or any component of the formulation. Caution is also advised for patients with severe hepatic impairment, and it should be avoided in conjunction with contraindicated drug combinations listed under major interactions.
Information provided on this page is for educational use by procurement and clinical professionals. Always consult a licensed healthcare provider for medical advice and prescribing decisions. GNH USA supplies this product subject to applicable regulatory and licensing requirements.
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Product details

Drug
Levocetirizine Dihydrochloride
Route
Oral Use
Manufacturer
Pharmachemie Bv
Origin
EU

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