Europe — EMA
Levocetirizina Stada (Levocetirizine)
GNH USA supplies Levocetirizina Stada (Levocetirizine), a H1 receptor antagonist for allergic rhinitis and chronic idiopathic urticaria.
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What is Levocetirizine?
Levocetirizine, the active ingredient in Levocetirizina Stada, is a H1 receptor antagonist presented as an oral dosage form for oral use. It alleviates symptoms of allergic rhinitis and chronic idiopathic urticaria in adults and adolescents. GNH USA supplies Levocetirizina Stada as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.
What is Levocetirizine used for?
Levocetirizine acts on peripheral H1 histamine receptors to control allergic disease manifestations. Allergic rhinitis: reduces nasal congestion, itching, sneezing and watery discharge. Chronic idiopathic urticaria: diminishes the frequency and severity of hives and associated itching.
What are the side effects of Levocetirizine?
Levocetirizine is generally well tolerated, but adverse reactions can occur.
Common Side Effects: - Drowsiness or mild sedation. - Dry mouth. - Headache. - Fatigue. - Nausea.
Serious or Rare Side Effects: - Angioedema or swelling of the face, lips, tongue. - Anaphylactic reactions requiring emergency care. - Severe skin eruptions such as Stevens‑Johnson syndrome. - Thrombocytopenia or significant drop in platelet count. - Hepatic enzyme elevations.
What precautions apply to Levocetirizine?
Before initiating therapy, consider patient‑specific factors and safety measures. Assess renal function: dose may need adjustment in severe impairment. Use caution in hepatic disease: monitor liver enzymes if clinically indicated. Avoid operating machinery or driving if drowsiness occurs. Pregnancy and breastfeeding: consult a healthcare professional before use. Store at room temperature: keep in the original container, protect from moisture and direct sunlight.
What does Levocetirizine interact with?
Levocetirizine may interact with other medicines that affect its metabolism or enhance sedation.
Major Interactions (Avoid): - Ketoconazole: can increase levocetirizine plasma concentrations. - Erythromycin: may raise systemic exposure. - Ritonavir: potent CYP3A4 inhibition may elevate levels.
Moderate Interactions (Monitor Closely): - Alcohol: additive central nervous system depression. - Other antihistamines or sedatives: may increase drowsiness. - Theophylline: levocetirizine can reduce its clearance, requiring monitoring.



