Levocetirizina Krka

Levocetirizine, the active ingredient in Levocetirizina Krka, is a second‑generation antihistamine presented as a tablet for oral use. It reduces allergic symptoms such as sneezing, itching and hives in adults and children with allergic rhinitis or chronic idiopathic urticaria.

GNH USA supplies Levocetirizina Krka as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Levocetirizine is used to manage allergic conditions that involve histamine‑mediated responses. - Allergic rhinitis: alleviates nasal congestion, sneezing and itching. - Chronic idiopathic urticaria: reduces the frequency and severity of hives and itching. - Allergic conjunctivitis: relieves eye itching, redness and tearing.

Levocetirizine may cause adverse reactions, which are generally mild but can be serious in rare cases.

Common Side Effects: - Drowsiness: mild sleepiness, especially at treatment initiation. - Dry mouth: reduced salivation leading to throat discomfort. - Headache: transient cranial pain of varying intensity. - Fatigue: generalized lack of energy.

Serious or Rare Side Effects: - Anaphylaxis: severe, potentially life‑threatening allergic reaction requiring immediate medical attention. - Severe skin reactions: such as Stevens‑Johnson syndrome or toxic epidermal necrolysis, presenting with widespread rash and mucosal involvement.

Levocetirizine should be used with caution in certain situations. - Dose adjustment in renal impairment: reduce dose according to renal function. - Avoid alcohol: may increase sedation. - Caution in elderly: monitor for increased drowsiness. - Pregnancy and lactation: use only if clearly needed after risk assessment. - Store at ambient temperature below 25°C: keep in the original pack, protect from moisture.

Levocetirizine may interact with other medicines.

Major Interactions (Avoid): - Strong CYP3A4 inhibitors (e.g., ketoconazole): may increase levocetirizine plasma levels. - Alcohol and CNS depressants: additive sedation. - Ritonavir: may raise exposure and risk of side effects.

Moderate Interactions (Monitor Closely): - Theophylline: may reduce antihistamine effectiveness. - Anticholinergic drugs: may increase dry‑mouth sensation. - Other antihistamines: risk of additive antihistaminic effects.