GNH USA

Europe — EMA

Levocetirizina

GNH USA supplies Levocetirizina (Levocetirizine), an antihistamine for allergic rhinitis and chronic urticaria. Request a quote for global supply today.

Levocetirizine Dihydrochloride

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What is Levocetirizine Dihydrochloride?

Levocetirizine, the active ingredient in Levocetirizina, is an antihistamine presented as an oral dosage form for oral use. It reduces symptoms of allergic rhinitis and chronic urticaria by blocking peripheral H1 receptors, and is prescribed for adults and children under medical supervision.

GNH USA supplies Levocetirizina as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide. The company adheres to stringent quality standards and provides regulatory‑approved batches to meet global demand. Customers benefit from reliable supply chains, comprehensive documentation, and responsive technical support throughout the procurement process.

What is Levocetirizine Dihydrochloride used for?

Levocetirizine is used to manage allergic conditions by antagonising peripheral H1 receptors.

Allergic rhinitis: alleviates sneezing, nasal congestion, itching and rhinorrhoea associated with seasonal or perennial triggers. Chronic urticaria: reduces the frequency and intensity of hives and associated itching. Seasonal allergic rhinitis: provides symptom control during pollen‑driven allergy periods.

What are the side effects of Levocetirizine Dihydrochloride?

Levocetirizine is generally well tolerated, but adverse reactions can occur.

Common Side Effects: - Drowsiness or mild sedation. - Dry mouth. - Headache. - Fatigue. - Nausea. - Dizziness.

Serious or Rare Side Effects: - Severe allergic reaction (anaphylaxis). - Thrombocytopenia. - Hepatic enzyme elevation. - Cardiac arrhythmia (rare). - Angio‑edema. - Persistent or worsening rash.

What precautions apply to Levocetirizine Dihydrochloride?

Before initiating therapy, consider the following safety measures.

Pregnancy: consult a healthcare professional; safety data are limited. Breastfeeding: assess risk versus benefit with a clinician. Renal impairment: dose adjustment may be required under medical guidance. Elderly patients: monitor for increased sedation. Concomitant CNS depressants: avoid excessive drowsiness. Store at ambient temperature: keep below 25 °C, retain in original packaging and protect from moisture.

What does Levocetirizine Dihydrochloride interact with?

Levocetirizine may interact with other medicines; monitor accordingly.

Major Interactions (Avoid): - Strong CYP3A4 inhibitors (e.g., ketoconazole) – may increase plasma levels. - Alcohol or other sedatives – can potentiate drowsiness.

Moderate Interactions (Monitor Closely): - Anticholinergic agents – may exacerbate dry mouth. - Theophylline – possible additive CNS effects. - Rifampicin – may reduce levocetirizine exposure. - Certain antihypertensives – monitor blood pressure changes.

Frequently asked questions

What conditions is Levocetirizina used to treat?+
Levocetirizina is indicated for the symptomatic relief of allergic rhinitis, including seasonal and perennial forms, and for the management of chronic idiopathic urticaria. It helps reduce nasal congestion, sneezing, itching, and the appearance of hives.
How does Levocetirizine work in the body?+
Levocetirizine selectively blocks peripheral histamine H1 receptors. By preventing histamine from binding to these receptors on mast cells, basophils and sensory nerves, it diminishes vasodilation, increased vascular permeability, and nerve stimulation, which are responsible for allergy‑related symptoms.
What is the usual dose of Levocetirizina?+
The dosage of Levocetirizina is determined by the prescribing healthcare professional based on the patient’s age, weight, renal function and the severity of symptoms. Patients should follow the prescriber’s instructions and not adjust the dose on their own.
Is Levocetirizina safe during pregnancy or breastfeeding?+
Safety data for Levocetirizina in pregnancy and lactation are limited. Women who are pregnant, planning to become pregnant, or breastfeeding should discuss potential risks and benefits with their healthcare provider before using the medication.
How do I order Levocetirizina from GNH USA?+
To place an order, submit an enquiry on the product page at gnh-usa.com specifying the required quantity. GNH USA works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.
How does Levocetirizina compare with other antihistamines?+
Levocetirizina is the active enantiomer of cetirizine, offering similar efficacy with a potentially lower incidence of sedation. Compared with first‑generation antihistamines, it provides better selectivity for H1 receptors and fewer anticholinergic side effects, making it a preferred choice for many patients.
What are the recommended storage conditions for Levocetirizina?+
Levocetirizina should be stored at ambient temperature, preferably below 25 °C. Keep the product in its original packaging, protect it from moisture and direct sunlight, and ensure the container is tightly closed to maintain stability.
How is Levocetirizina administered?+
Levocetirizina is taken orally, usually as a tablet or oral solution, with or without food. The exact form and administration instructions are provided by the prescriber and should be followed precisely.
What are the most serious risks associated with Levocetirizina?+
Serious adverse reactions, although rare, include anaphylaxis, severe skin reactions such as angio‑edema, thrombocytopenia, and significant hepatic enzyme elevations. Patients should seek immediate medical attention if they experience any signs of a severe allergic reaction.
Who should not use Levocetirizina?+
Levocetirizina is contraindicated in individuals with known hypersensitivity to levocetirizine or any of its excipients. Caution is advised for patients with severe renal impairment, and it should be used only under medical supervision in pregnant or breastfeeding women.
Information provided on this page is for educational use by procurement and clinical professionals. Always consult a licensed healthcare provider for medical advice and prescribing decisions. GNH USA supplies this product subject to applicable regulatory and licensing requirements.

Product details

Drug
Levocetirizine Dihydrochloride
Route
Oral Use
Manufacturer
Ratiopharm-Comercio E Industria De Produtos Farmaceuticos Lda
Origin
EU

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